Female ReproAdvancing Research and Ensuring Reproductive Health

Explore recent research and guidelines on factors impacting fertility, reproductive health, and aging in women.

Endocrine Society Experts Issue Clinical Practice Guideline on Hypothalamic Amenorrhea
March 22, 2017 | Female athletes and women who have eating disorders are prone to developing a condition called hypothalamic amenorrhea that causes them to stop menstruating. The Endocrine Society today issued…

Tri-Point: The Genetics and Epigenetics of Puberty
January 2017 | In 2005, the editors of Science, celebrating the journal’s 125th anniversary, posed 125 unanswered questions that it predicted would fuel active research…

Survey: Endocrinologists Want Training in Transgender Care
January 10, 2017 | Four out of five physicians who specialize in treating hormone health conditions have never received formal training on care for transgender individuals, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism

Women Dissatisfied with Long Process to Diagnose Polycystic Ovary Syndrome
December 1, 2016 | International survey finds many wait years for diagnosis of common reproductive, metabolic health problem. A large international survey of women with a common condition called…

Endocrine Society Meets with NIH Office of Research on Women’s Health to Discuss Research Gaps & Policy Priorities
December 2016 | On Thursday, December 1, Janine Austin Clayton, MD, director of the NIH Office of Research on Women’s Health (ORWH) and associate director of Women’s Health Research…

Underdiagnosed & Undertreated: The Mysteries of Genitourinary Syndrome of Menopause
December 2016 | Most women have never heard of genitourinary syndrome of menopause. But given its prevalence and progressive nature, many physicians are working to increase attention and treatment…

Menopausal Hormone Therapy Improves Bone Health
November 17, 2016 | Study reveals bone density, structure benefits persist after treatment ends. Women who undergo hormone therapy for menopausal symptoms such as hot flashes can not only increase…

Customized Vitamin D Supplements May Benefit Pregnant Women
October 27, 2016 | Doses can be tailored to compensate for individual risk factors, protect bone health. Individualized supplement doses help protect pregnant women from vitamin D deficiency, according…

Resveratrol Can Help Correct Hormone Imbalance in Women with PCOS
October 18, 2016 | Supplement lowers testosterone levels in women with common cause of infertility. Resveratrol—a natural compound found in red wine and grapes—can help address a hormone imbalance…

Bioengineering the Human Ovary
ENDO Session | No credit available
Teresa K. Woodruff, PhD
Learn about discoveries in “oncofertility” and novel lab techniques to model natural gonadal tissue for hormone restoration.

Neurobiology of Sexual Function and Dysfunction in Women
ENDO Session | No credit available
Margaret E. Wierman, MD
Where are we in understanding the wiring of sexual function in women? Hear about the role of sex hormones in signaling and desire, and how it differs from male biology.

Transitions of Care: Turner Syndrome
Practice Resource | No credit available
Resources for you and your patients to facilitate the challenging transition from pediatric to adult endocrine practice.

Women’s Health Digital Toolkit
Patient Resource | No credit available
Reviewer: Genevieve S Neal-Perry, MD, PhD
Interactive and downloadable resources and information for patients with questions related to women’s health including menopause, bone loss, and estrogen.

Whole-exome Sequencing for Diagnosis of Turner Syndrome: Towards Next Generation Sequencing and Newborn Screening
JCEM | January 24, 2017
David R. Murdock, Frank X. Donovan, Settara C. Chandrasekharapp, Nicole Banks, Carolyn Bondy, Maximilian Muenke, and Paul Kruszka
Context: Turner syndrome (TS) is due to a complete or partial loss of an X chromosome in females and is not currently part of newborn screening…

Gestational Hyperandrogenism in Developmental Programming
Endocrinology | December 14, 2016
Christopher Hakim, Vasantha Padmanabhan, and Arpita K. Vyas
Developmental programming is a complex process whereby perturbed intrauterine environment during a critical…

Delayed Diagnosis and a Lack of Information Associated With Dissatisfaction in Women With Polycystic Ovary Syndrome
JCEM | December 01, 2016
Melanie Gibson-Helm, Helena Teede, Andrea Dunaif, and Anuja Dokras
Polycystic ovary syndrome (PCOS) is an endocrine condition affecting 9% to 18% of reproductive-aged women…

The Steroidogenic Acute Regulatory Protein (StAR) Is Regulated by the H19/let-7 Axis
Endocrinology | November 04, 2016
Yi Men, Yanhong Fan, Yuanyuan Shen, Lingeng Lu, and Amanda N. Kallen
Tight spatiotemporal control of steroid production is essential for multiple processes involved in reproduction and fertility…

Determinants of the Maternal 25-Hydroxyvitamin D Response to Vitamin D Supplementation during Pregnancy
JCEM | October 28, 2016
Rebecca J. Moon, Nicholas C. Harvey, Cyrus Cooper, Stefania D'Angelo, Sarah R. Crozier, Hazel M. Inskip, Inez Schoenmakers, Ann Prentice, Nigel K. Arden, Nicholas J. Bishop, Andrew Carr, Elaine M. Dennison, Richard Eastell, Robert Fraser, Saurabh V. Gandhi, Keith M. Godfrey, Stephen Kennedy, M. Zulf Mughal, Aris T. Papageorghiou, David M. Reid, Sian M. Robinson, and M. Kassim Javaid
Context: Current approaches to antenatal vitamin D supplementation do not account for interindividual differences in 25-hydroxyvitamin D (25(OH)D) response. Objective: We assessed which maternal and…

Independent Contributions of Nocturnal Hot Flashes and Sleep Disturbance to Depression in Estrogen-Deprived Women
JCEM | September 28, 2016
Hadine Joffe, Sybil L. Crawford, Marlene P. Freeman, David P. White, Matt T. Bianchi, Semmie Kim, Nicole Economou, Julie Camuso, Janet E. Hall and Lee S. Cohen
Context: Women are at increased risk for mood disturbance during the menopause transition. Hot flashes (HFs), sleep disruption, and fluctuating estradiol levels correlate with menopause-associated depression…

Identification of Multiple Gene Mutations Accounts for a new Genetic Architecture of Primary Ovarian Insufficiency
JCEM | September 7, 2016
Justine Bouilly, Isabelle Beau, Sara Barraud, Valérie Bernard, Kemal Azibi, Jérôme Fagart, Anne Fèvre, Anne Laure Todeschini, Reiner A. Veitia, Chérif Beldjord, Brigitte Delemer, Catherine Dodé, Jacques Young, and Nadine Binart
Context: Idiopathic primary ovarian insufficiency (POI) is a major cause of amenorrhea and infertility. POI affects 1% of women before age 40 years, and several…

Impact of Levothyroxine in Miscarriage and Preterm Delivery Rates in First Trimester Thyroid Antibody-Positive Women with TSH Less Than 2.5 mIU/L
JCEM | July 26, 2016
Roberto Negro, Alan Schwartz, and Alex Stagnaro-Green
Thyroid disease during pregnancy is associated with multiple adverse maternal and fetal outcomes. In particular, multiple observational studies have demonstrated an association between the presence…

Hormone Replacement Therapy versus the Combined Oral Contraceptive Pill in Premature Ovarian Failure: A Randomized Controlled Trial of the Effects on Bone Mineral Density
JCEM | June 24, 2016
Beth Cartwright, Jillian Robinson, Paul T. Seed, Ignac Fogelman and Janice Rymer
Context: Women with premature ovarian failure (POF) face many years of estrogen deficiency. One of the major consequences is bone loss. The optimal form of estrogen…

Hypothalamic Amenorrhea
JCEM | March 22, 2017
Catherine M. Gordon, Kathryn E. Ackerman, Sarah L. Berga, Jay R. Kaplan, George Mastorakos, Madhusmita Misra, M. Hassan Murad, Nanette F. Santoro, and Michelle P. Warren
FHA is a form of chronic anovulation, not due to identifiable organic causes, but often associated with stress, weight loss, excessive exercise, or a combination thereof. Investigations should include assessment of systemic and endocrinologic etiologies…

Treatment of Symptoms of the Menopause
JCEM | October 7, 2015
Cynthia A. Stuenkel, Susan R. Davis, Anne Gompel, Mary Ann Lumsden, M. Hassan Murad, JoAnn V. Pinkerton, and Richard J. Santen
Menopausal hormone therapy (MHT) is the most effective treatment for vasomotor symptoms and other symptoms of the climacteric. Benefits may exceed risks for the majority…

Androgen Therapy in Women: A Reappraisal
JCEM | October 3, 2014
Margaret E. Wierman, Wiebke Arlt, Rosemary Basson, Susan R. Davis, Karen K. Miller, Mohammad H. Murad, William Rosner, and Nanette Santoro
We continue to recommend against making a diagnosis of androgen deficiency syndrome in healthy women because there is a lack of a well-defined syndrome, and…

Diagnosis and Treatment of Polycystic Ovary Syndrome
JCEM | November 20, 2013
Richard S. Legro, Silva A. Arslanian, David A. Ehrmann, Kathleen M. Hoeger, M. Hassan Murad, Renato Pasquali, and Corrine K. Welt
We suggest using the Rotterdam criteria for diagnosing PCOS (presence of two of the following criteria: androgen excess, ovulatory dysfunction, or polycystic ovaries). Establishing a…

Endocrine Treatment of Transsexual Persons
JCEM | April 30, 2011
Wylie C. Hembree, Peggy Cohen-Kettenis, Henriette A. Delemarre-van de Waal, Louis J. Gooren, Walter J. Meyer, III, Norman P. Spack, Vin Tangpricha, and Victor M. Montori
Transsexual persons seeking to develop the physical characteristics of the desired gender require a safe, effective hormone regimen that will 1) suppress endogenous hormone secretion…

Evaluation and Treatment of Hirsutism in Premenopausal Women
JCEM | January 14, 2009
Kathryn A. Martin, R. Jeffrey Chang, David A. Ehrmann, Lourdes Ibanez, Rogerio A. Lobo, Robert L. Rosenfield, Jerry Shapiro, Victor M. Montori, and Brian A. Swiglo
We suggest testing for elevated androgen levels in women with moderate or severe hirsutism or hirsutism of any degree when it is sudden in onset, rapidly progressive…

ENDO 2017 Preconference
Androgen Excess and PCOS Society Update

Dates: March 31, 2017
Location: Orlando, Florida, United States
Sponsor: Androgen Excess and PCOS Society

Frontiers in Reproduction
Dates: April 26 - June 17, 2017
Sponsor: Marine Biological Laboratory - The University of Chicago
Location: Woods Hole, Massachusetts , United States

7th International IVI Congress
Dates: May 11 - 13, 2017
Location: Bilbao, Spain
Sponsor: IVI Congress

ART World Congress
Dates: October 25-26, 2017
Sponsor: CME Congresses Ltd.
Location: New York, New York, United States

Society for the Study of Reproduction 2017 Annual Meeting
Dates: July 13 - 16, 2017
Location: Washington, DC, United States
Sponsor: Society for the Study of Reproduction

2017 American Society for Reproductive Medicine Congress and Expo
Dates: October 28 - November 1, 2017
Location: Washington, DC, United States
Sponsor: American Society for Reproductive Medicine

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