ThyroidNew Guidelines, Testing, and Treatments

Hear the latest news, learn about exciting research, and apply guidelines to stay at the leading edge of understanding and treating thyroid disease at a time of changing standards in diagnosis and care.

Patients with Heart Failure, Subclinical Hypothyroidism Have Worse Outcomes
April 2, 2017 | Patients with more severe heart failure have higher levels of the thyroid hormones TSH and T4 and lower T3 levels, and those with higher T4 levels…

People with Higher Thyroid Hormone Levels May be at Greater Risk for Atherosclerosis
April 1, 2017 | Middle-aged and elderly people with higher free thyroxine levels may be more likely to develop atherosclerotic diseases, new research from the Netherlands…

Recent Thyroid Cancer Trends in the United States Suggest Age, Racial Disparities
April 1, 2017 | In the United States, thyroid cancer incidence is rising among young people as well as Hispanics and African Americans, a new study reports. Results of this research…

Cow's Milk Interferes with Absorption of Thyroid Supplement Levothyroxine
April 1, 2017 | Taking the common oral thyroid hormone medication levothyroxine with a glass of cow’s milk significantly decreases the body’s ability to absorb the drug, a preliminary study finds…

Unique Biomarkers Identified for Use in Thyroid Cancer Follow-Up
January 2017 | Researchers have identified two unique biomarkers that show promise for monitoring patients who have received treatment for papillary thyroid cancer (PTC), according to a study recently published in the new open access Journal of the Endocrine Society…

Commentary: The Risk of Hypothyroidism in Some Thyroid Cancer Patients
January 2017 | The American Cancer Society estimates that among the 62,450 people who will be diagnosed with thyroid cancer in 2016, some will be treated with thyroidectomy…

New Thyroid Surgery Technique Leaves No Visible Scar, but Experts Warn Caution
January 2017 | A new endoscopic thyroidectomy procedure eliminates visible scars, but endocrine experts caution that the outcomes may not be the same as traditional surgeries…

Saving Face: Why Patients Seek Robotic Thyroidectomy
October 2016 | Although it’s an “off-label” procedure that has only been mastered by a handful of surgeons in the US, some patients are opting for a robotic transaxillary thyroidectomy…

Probability Data Could Better Direct Lymph Node Removal for Thyroid Cancer
August 2016 | Surgeons operating on patients with advanced thyroid cancer are often conflicted when deciding how many lymph nodes they should remove to reduce the patient’s risk of recurrence…

Fairytales: Dispelling Pediatric Thyroid Cancer Myths
June 2015 | Misrepresentations surround the occurrence, causes, and treatment of thyroid cancer in the pediatric patient population. It’s not as “rare” as once thought, and despite its treatability…

Explore highlights of current education across the Endocrine Society.


New Treatments for Advanced Thyroid Cancer
CEU Satellite Symposium | 1.0 AMA PRA Category 1 Credits™
Lori J. Wirth, MD
Learn which patients are most likely to benefit from new MKI therapies and how to optimize treatment.

Congenital Hypothyroidism Practice Improvement Module: Diagnosis and Management
Practice Resource | 20 AMA PRA Category 1 Credits™ and ABIM MOC Part 4 points
Faculty: Rosalind S. Brown MD; Stephen LaFranchi, MD; Susan R. Rose, MD; and Ari Wassner, MD
Improve your screening and care for pediatric patients with primary CH using updated performance measures. Developed in partnership with the Pediatric Endocrine Society.

Interpretation of Challenging Thyroid Function Tests
ENDO Session | No credit available
Victor Joseph Bernet, MD
What can you do when there isn’t a conclusive answer? Follow case-based discussions to learn about tools and tricks to thyroid testing.

Ultrasound and Molecular Diagnostics in the Evaluation of Thyroid Nodules
ENDO Session | No credit available
Jennifer Anne Sipos, MD
Updated guideline discussion on risk stratification, cytology, and molecular diagnostics to manage practice challenges in assessing thyroid nodules.

Thyroid Digital Toolkit
Patient Resource | No credit available
Reviewer: Alan P. Farwell, MD
Interactive and downloadable resources and information for patients with questions about thyroid health and disease.

Thyroid Ultrasound Workshops 2016
Workshop Webcast | 9.0 AMA PRA Category 1 Credits™ and ABIM MOC Part 2 points
Introductory Planning Chairs: Jennifer Sipos, MD and Joshua P. Klopper, MD
Advanced Planning Chair: Susan J. Mandel, MD, MPH
Improve your ultrasound skills with lessons on techniques for FNA and diagnostic testing, as well as guides to interpreting challenging results.

Endocrine Facts & Figures: Thyroid
Research Resource | No credit available
Advisory Panel Chair: Robert A. Vigersky, MD
Updated epidemiological data and in-depth discussion on several types of thyroid disease with current citations and expert insights.

Explore highlights of current publications across the Endocrine Society journals. Visit academic.oup.com/endocrinesociety for more.


Long-Term Quality of Life in Adult Survivors of Pediatric Differentiated Thyroid Carcinoma
JCEM | December 21, 2016
Marloes Nies, Mariëlle S. Klein Hesselink, Gea A. Huizinga, Esther Sulkers, Adrienne H. Brouwers, Johannes G. M. Burgerhof, Eveline W. C. M. van Dam, Bas Havekes, Marry M. van den Heuvel-Eibrink, Eleonora P. M. Corssmit, Leontien C. M. Kremer, Romana T. Netea-Maier, Heleen J. H. van der Pal, Robin P. Peeters, John T. M. Plukker, Cécile M. Ronckers, Hanneke M. van Santen, Wim J. E. Tissing, Thera P. Links, and Gianni Bocca
The diagnosis and treatment of childhood cancer constitute a major life event that may influence psychosocial functioning and quality of life (QoL) long after initial treatment has been completed. Pediatric differentiated thyroid carcinoma (DTC) is a rare…

The Relationship Between Thyroid Function and the Prevalence of Type 2 Diabetes Mellitus in Euthyroid Subjects
JCEM | December 01, 2016
Yeqing Gu, Huihui Li, Xue Bao, Qing Zhang, Li Liu, Ge Meng, Hongmei Wu, Huanmin Du, Hongbin Shi, Yang Xia, Qian Su, Liyun Fang, Fei Yu, Huijun Yang, Bin Yu, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Qi Guo, Hong Chang, Guolin Wang, Guowei Huang, Kun Song, and Kaijun Niu
Type 2 diabetes mellitus (T2DM) is the most common chronic endocrine disease, characterized by hyperglycemia resulting from impaired insulin secretion…

Targeting Autophagy Sensitizes BRAF-Mutant Thyroid Cancer to Vemurafenib
JCEM | October 18, 2016
Weibin Wang, Helen Kang, Yinu Zhao, Irene Min, Brian Wyrwas, Maureen Moore, Lisong Teng, Rasa Zarnegar, Xuejun Jiang, and Thomas J. Fahey, III
Thyroid cancer incidence has increased significantly in recent years, and it is currently the fifth most frequently diagnosed…

Long-Term Recurrence of Small Papillary Thyroid Cancer and Its Risk Factors in a Korean Multicenter Study
JCEM | October 12, 2016
Yul Hwangbo, Jung Min Kim, Young Joo Park, Eun Kyung Lee, You Jin Lee, Do Joon Park, Young Sik Choi, Kang Dae Lee, Seo Young Sohn, Sun Wook Kim, Jae Hoon Chung, Dong Jun Lim, Min Hee Kim, Min Joo Kim, Young Suk Jo, Min Ho Shong, Sung-Soo Koong, Jong Ryeal Hahm, Jung Hwa Jung, and Ka Hee Yi
Thyroid cancer is the most common malignancy in Korea. According to the statistics of the Korea Central Cancer Registry…

Clinical, Sonographic, and Pathological Characteristics of RAS-Positive versus BRAF-Positive Thyroid Carcinoma
JCEM | September 30, 2016
Sujay Kakarmath, Howard T. Heller, Caroline A. Alexander, Edmund S. Cibas, Jeffrey F. Krane, Justine A. Barletta, Neal I. Lindeman, Mary C. Frates, Carol B. Benson, et. al., Atul A. Gawande, Nancy L. Cho, Matthew Nehs, Francis D. Moore, Ellen Marqusee, Mathew I. Kim, P. Reed Larsen, Norra Kwong, Trevor E. Angell, and Erik K. Alexander
Mutations in the BRAF and RAS oncogenes are responsible for most well-differentiated thyroid cancer. Yet, our clinical understanding of how BRAF-positive and RAS-positive thyroid cancers…

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies
JCEM | September 30, 2016
Carole Rieben, Daniel Segna, Bruno R. da Costa, Tinh-Hai Collet, Layal Chaker, Carole E. Aubert, Christine Baumgartner, Osvaldo P. Almeida, Eef Hogervorst, Stella Trompet, Kamal Masaki, Simon P. Mooijaart, Jacobijn Gussekloo, Robin P. Peeters, Douglas C. Bauer, Drahomir Aujesky, and Nicolas Rodondi
Although both overt hyper- and hypothyroidism are known to lead to cognitive impairment, data on the association between subclinical thyroid dysfunction and cognitive function are conflicting…

Papillary Thyroid Carcinoma With Rare Exon 15 BRAF Mutation Has Indolent Behavior: A Single-Institution Experience
JCEM | August 29, 2016
Liborio Torregrossa, David Viola, Elisa Sensi, Mirella Giordano, Paolo Piaggi, Cristina Romei, Gabriele Materazzi, Paolo Miccoli, Rossella Elisei, and Fulvio Basolo
The large majority of thyroid cancer is represented by papillary thyroid carcinoma (PTC), which accounts for more than 80% of all thyroid malignancies. BRAF is a member of the RAF kinase…

IL-17A Exacerbates Fibrosis by Promoting the Proinflammatory and Profibrotic Function of Orbital Fibroblasts in TA
JCEM | August 1, 2016
Sijie Fang, Yazhuo Huang, Shuaiwei Wang, Yidan Zhang, Xuerui Luo, Luyan Liu, Sisi Zhong, Xingtong Liu, Dan Li, Rui Liang, Piccioni Miranda, Ping Gu, Huifang Zhou, Xianqun Fan, and Bin Li
Thyroid-associated ophthalmopathy (TAO) is the most common disorder of the orbit, which is a sight-threatening autoimmune ocular disease. As the most common extrathyroidal complication of Graves' disease…

Impact of Levothyroxine in Miscarriage and Preterm Delivery Rates in First Trimester Thyroid Antibody-Positive Women With TSH Less Than 2.5 mIU/L
JCEM | July 26, 2016
Roberto Negro, Alan Schwartz, and Alex Stagnaro-Green
Thyroid disease during pregnancy is associated with multiple adverse maternal and fetal outcomes. In particular, multiple observational studies have demonstrated an association between the presence…

Factitious Graves' Disease Due to Biotin Immunoassay Interference—A Case and Review of the Literature
JCEM | June 30, 2016
Marianne S. Elston, Shekhar Sehgal, Stephen Du Toit, Tania Yarndley, and John V. Conaglen
Biotin (vitamin B7) is an essential co-factor for four carboxylases involved in fatty acid metabolism, leucine degradation, and gluconeogenesis. The recommended daily intake (RDI) of biotin…

For a complete list of Endocrine Society guidelines, visit endocrine.org/guidelines.


Management of Thyroid Dysfunction during Pregnancy and Postpartum
JCEM | July 2, 2013
Leslie De Groot, Marcos Abalovich, Erik K. Alexander, Nobuyuki Amino, Linda Barbour, Rhoda H. Cobin, Creswell J. Eastman, John H. Lazarus, Dominique Luton, Susan J. Mandel, Jorge Mestman, Joanne Rovet, and Scott Sullivan
Practice guidelines are presented for diagnosis and treatment of patients with thyroid-related medical issues just before and during pregnancy and in the postpartum interval. These include evidence-based…

For additional meetings, visit the Endocrine Society’s Worldwide Endocrinology Calendar at endocrine.org/calendar.


Clinical Endocrinology Update & Endocrine Board Review
Dates: September 23–27, 2017
Location: Chicago, Illinois, United States
Sponsor: Endocrine Society
Whether you need the latest clinical information or you’re preparing to certify or recertify for the boards, Clinical Endocrinology Update (CEU) and Endocrine Board Review (EBR) have you covered.

87th Annual Meeting of the American Thyroid Association
Dates: October 18 - 22, 2017
Location: Victoria, BC, Canada
Sponsor: American Thyroid Association

ENDO Bridge
Dates: October 19–22, 2017
Location: Antalya, Turkey
Sponsor: Endocrine Society, the European Society of Endocrinology, and The Society of Endocrinology and Metabolism of Turkey
EndoBridge will provide a comprehensive update in the field of endocrinology for the clinical endocrinologist. The official language of the meeting is English, but simultaneous translation will be available in Russian, Arabic, and Turkish

ENDO 2018
Dates: March 17–20, 2018
Location: Chicago, Illinois, United States
Sponsor: Endocrine Society
ENDO is the world’s largest event for presenting and obtaining the latest in endocrine science and medicine with an extensive program covering a broad array of topics, various networking opportunities, poster sessions, updates on new products and technologies at the ENDOExpo, and more.

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