Obesity and Appetite Regulation


Supporting Advances in Understanding, Preventing, and Treating Obesity

Learn about the causes and considerations when treating obesity, and hear about research, healthcare, and policy are changing the landscape.

Gut Bacteria Differ Between Obese and Lean Youth
September 20, 2016 | Study is first to find link between gut flora and fat distribution in children, teens. Children and teenagers who are obese have different microorganisms living…

Forbidden Fruits: The Endocrine-Disrupting Threat of “Obesogens”
August 2016 | Endocrine-disrupting chemicals known as “obesogens,” found in many fungicides, have been shown to alter the function of fat cells in animal studies. Are fruits and vegetables…

Hunt for New Obesity Pills | BBC News
March 2015 | Two promising approaches to finding effective weight loss drugs have been presented at the annual meeting of the Endocrine Society. Animals given one experimental drug…

Obesity Management: Optimizing Care of Your Patients
CEU Satellite Symposium | 1.0 AMA PRA Category 1 Credits™
Ken Fujioka, MD
Follow patient cases to learn tactics to assess and treat your patients with obesity, as well as useful communication approaches.

Incorporating Lifestyle Changes into Obesity Management
ENDO Session | No credit available
Daniel H. Bessesen, MD
Practical tactics to have productive conversations and counsel your patient to overcome the significant challenges in changing lifestyle.

Treatment of Obesity in Diabetes
ENDO Session | No credit available
W. Timothy Garvey, MD
“Diabetes is not an isolated entity.” Learn clinical relationships between obesity and diabetes that influence treatment strategies in the larger spectrum of cardiometabolic disease.

Mechanisms Underlying Weight Loss with Bariatric Surgery: Lessons from Animal Models
ENDO Session | No credit available
Randy J. Seeley, PhD
Hear how animal models are shedding light on how bariatric surgery affect weight loss as well as many other metabolic outcomes.

Genetic Contributions to Outcomes after Bariatric Surgery
ENDO Session | No credit available
Lee M. Kaplan, MD, PhD
Learn about genetic studies being used to understand the underlying effects of metabolic surgery and act as clinical outcome predictors.

Endocrine Facts & Figures: Obesity
Research Resource | No credit available
Advisory Panel Chair: Robert A. Vigersky, MD
Updated epidemiological data and in-depth discussion on obesity, metabolic syndrome, and associated comorbidities with current citations and expert insights.

Obesity Management Workshop 2016
Workshop Webcast | 9.75 AMA PRA Category 1 Credits™ and ABIM MOC Part 2 points
Planning Chairs: Richard Atkinson, Jr., MD; Daniel Bessesen, MD; Marc-Andre Cornier, MD; and William T. Donahoo, MD
Expert faculty focus on advanced practice challenges and highlight emerging therapies and strategies for preventing, diagnosing, and managing obesity.

Pediatric Obesity: The Hidden High Costs of Junk Food
Patient Resource | No credit available
Interactive and downloadable infographic for patients and caregivers with questions about how children’s food choices can affect health and healthcare costs.

Bariatric Surgery and Adolescents
Patient Resource | No credit available
Interactive and downloadable infographic for caregivers with questions about bariatric surgery is an option for their child.

Robust Reductions of Excess Weight and Hyperphagia by Beloranib in Rat Models of Genetic and Hypothalamic Obesity
Endocrinology | November 16, 2016
Clinton T. Elfers and Christian L. Roth
Hypothalamic lesions or deficient melanocortin (MC) signaling via MC4 receptor (MC4r) mutations often lead to hyperphagia and severe treatment-resistant obesity. We tested the methionine aminopeptidase…

Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity
JCEM | October 7, 2016
Stefan Z. Lutz, Andreas Peter, Fausto Machicao, Apostolia Lamprinou, Jürgen Machann, Fritz Schick, Ingmar Königsrainer, Alfred Königsrainer, Andreas Fritsche, Harald Staiger, Hans-Ulrich Häring, Norbert Stefan, and Konstantinos Kantartzis
Acute pharmacological inhibition of 11β-hydroxysteroid-dehydrogenase 1 (11β-HSD1), which converts cortisone into the much more potent cortisol in peripheral tissues, results in reduction of total, visceral…

Free Radical-derived Oxysterols: Novel Adipokines Modulating Adipogenic Differentiation of Adipose Precursor Cells
JCEM | October 6, 2016
Giuseppe Murdolo, Marta Piroddi, Cristina Tortoioli, Desirée Bartolini, Martin Schmelz, Francesca Luchetti, Barbara Canonico, Stefano Papa, Chiara Zerbinati, Luigi Iuliano, and Francesco Galli
Increased oxidative stress in adipose tissue emerges as an inducer of obesity-linked insulin resistance. Here we tested whether free-radical derived oxysterols are formed by, and accumulate…

Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood
JCEM | September 7, 2016
Rebecca A. Ohman-Hanson, Melanie Cree-Green, Megan M. Kelsey, Daniel H. Bessesen, Teresa A. Sharp, Laura Pyle, Rocio I. Pereira, and Kristen J. Nadeau
Insulin resistance (IR) and type 2 diabetes are increasing, particularly in Hispanic (H) vs non-Hispanic White (NHW) populations. Adiponectin has a known role in IR, and therefore…

Risk Factors for Spontaneously Self-Reported Postprandial Hypoglycemia After Bariatric Surgery
JCEM | June 23, 2016
Monica Nannipieri, Anna Belligoli, Daniela Guarino, Luca Busetto, Diego Moriconi, Roberto Fabris, Andrea Mari, Simona Baldi, Marco Anselmino, Mirto Foletto, Roberto Vettor, and Ele Ferrannini
Postprandial hypoglycemia (PPHG) is a recognized complication of Roux-en-Y gastric bypass (RYGB) surgery. Data on PPHG after laparoscopic sleeve gastrectomy (LSG) are scant. The objective…

Cannabinoid Receptor 2 as Antiobesity Target: Inflammation, Fat Storage, and Browning Modulation
JCEM | June 13, 2016
F. Rossi, G. Bellini, L. Luongo, I. Manzo, S. Tolone, C. Tortora, M. E. Bernardo, A. Grandone, A. Conforti, L. Docimo, B. Nobili, L. Perrone, F. Locatelli, S. Maione, and E. Miraglia del Giudice
Obesity is associated with a low-grade inflammatory state and adipocyte (ADP) hyperplasia/hypertrophy. Obesity inhibits the “browning” of white adipose tissue. Cannabinoid receptor 2 (CB2) agonists…

Effect of Three Levels of Dietary Protein on Metabolic Phenotype of Healthy Individuals With 8 Weeks of Overfeeding
JCEM | May 9, 2016
George A. Bray, Leanne M. Redman, Lilian de Jonge, Jennifer Rood and Steven R. Smith
Context: Obesity is associated with insulin resistance and other metabolic changes that might be modified by overfeeding diets with different protein levels. Objective: The objective…

Increased Bile Acid Synthesis and Impaired Bile Acid Transport in Human Obesity
JCEM | December 18, 2015
Rebecca A. Haeusler, Stefania Camastra, Monica Nannipieri, Brenno Astiarraga, Jose Castro-Perez, Dan Xie, Liangsu Wang, Manu Chakravarthy, and Ele Ferrannini
Alterations in bile acid (BA) synthesis and transport have the potential to affect multiple metabolic pathways in the pathophysiology of obesity. The objective of the study…

Obesity Is Associated With Low NAD+/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins
JCEM | November 17, 2015
Sakari Jukarainen, Sini Heinonen, Joel T. Rämö, Rita Rinnankoski-Tuikka, Elisabeth Rappou, Mark Tummers, Maheswary Muniandy, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Jaakko Kaprio, Aila Rissanen, Eija Pirinen, and Kirsi H. Pietiläinen
Sirtuins (SIRTs) regulate cellular metabolism and mitochondrial function according to the energy state of the cell reflected by NAD+ levels. Objective: Our aim was to…

Pharmacological Management of Obesity
JCEM | January 15, 2015
Caroline M. Apovian, Louis J. Aronne, Daniel H. Bessesen, Marie E. McDonnell, M. Hassan Murad, Uberto Pagotto, Donna H. Ryan, and Christopher D. Still
Weight loss is a pathway to health improvement for patients with obesity-associated risk factors and comorbidities. Medications approved for chronic weight management can be useful adjuncts…

Endocrine and Nutritional Management of the Post-Bariatric Surgery Patient
JCEM | April 30, 2011
David Heber, Frank L. Greenway, Lee M. Kaplan, Edward Livingston, Javier Salvador, and Christopher Still
Bariatric surgery is not a guarantee of successful weight loss and maintenance. Increasingly, patients regain weight, especially those undergoing restrictive surgeries such as laparoscopic banding…

Keystone Symposium on Obesity and Adipose Tissue Biology
Dates: January 22 - 26, 2017
Location: Keystone, Colorado, United States
Sponsor: Keystone Symposia on Molecular & Cellular Biology

Metabolic Syndrome Bench to Clinic
Dates: March 11, 2017
Location: Baltimore, Maryland, United States
Sponsor: Society of Toxicology

Sex and Gender Factors Affecting Metabolic Homeostasis and Diabetes and Obesity
Dates: March 19 - 23, 2017
Location: Tahoe City, California, United States
Sponsor: Keystone Symposia on Molecular and Cellular Biology

ENDO 2017 Preconference
Androgen Excess and PCOS Society Update

Dates: March 31, 2017
Location: Orlando, Florida, United States
Sponsor: Androgen Excess and PCOS Society

Keystone Symposium on Neuronal Control of Appetite and Metabolism and Weight
Dates: May 9 - 13, 2017
Location: Copenhagen, Denmark
Sponsor: Keystone Symposia on Molecular and Cellular Biology

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