Pediatric Endocrinology

Pediatric endocrinology

Dedicated to the Research and Treatment of Childhood Endocrine Disorders

Hear the latest news, learn about exciting research, and apply guidelines to stay at the leading edge of understanding and treating endocrine disorders, and bridging pediatric and adult care.

Survey: Endocrinologists Want Training in Transgender Care
January 10, 2017 | Four out of five physicians who specialize in treating hormone health conditions have never received formal training on care for transgender individuals, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism

Combination GH and Aromatase Inhibitor Therapy Increases Height Potential in Pubertal Boys with ISS
January 2017 | Combining aromatase inhibitors (AIs) and growth hormone (GH) was shown to increase the height potential in pubertal boys with idiopathic short stature (ISS) when compared to treating…

In Memoriam: Melvin M. Grumbach, MD
October 2016 | Endocrine Society past-president (1981- 1982) Melvin Malcom Grumbach, MD, known to the world as Mel, passed away October 4, 2016 at the age of 90…

Gut Bacteria Differ Between Obese and Lean Youth
September 20, 2016 | Study is first to find link between gut flora and fat distribution in children, teens. Children and teenagers who are obese have different microorganisms living…

Mind the Gap: Guiding Pediatric Patients into Adult Care
July 2016 | As a pediatric patient transitions to adult care, the challenges can be overwhelming, not just for the patients…but also for the clinician. Maneuvering through this often arduous…

Tipping the Scales: Couch Potato Kids & Diabetes in Adulthood
July 2016 | It’s not unusual when research proves the benefits of what parents have been telling kids for generations: “Go outside and play!” Mom was right: sedentary kids…

Hypophosphatasia: New Options in the Management of Alkaline Phosphatase Deficiency
ENDO Satellite Symposium | 2.0 AMA PRA Category 1 Credits™ and ABIM MOC Part 2 points
Chair: Jill H. Simmons, MD
Faculty: Nancy S. Dunbar, MD, MPH; Peter J. Tebben, MD; and Michael P. Whyte, MD
What does low alkaline phosphatase mean in practice? Recognize subtle signs of HPP in pediatric and adult patients and learn about the most recent treatment approvals.

Thyroid Nodules and Cancer Guidelines in Children
CEU Session | No credit available
Gary Lee Francis, MD, PhD
Are thyroid nodules in children actually as rare as we think? Hear the most recent updates in testing for malignancy and treating thyroid cancer in children.

Transgender Youth: Current Concepts and Priorities for Research
ENDO Session | No credit available
Stephen M. Rosenthal, MD
Hear about new concepts that question long held assumptions in this growing area of pediatric care.

Debate: Are There Long-Term Risks in Pediatric Growth Hormone Treatment?
ENDO Session | No credit available
Faculty: Alan D. Rogol, MD, PhD; Jean-Claude Carel, MD; and Ron G. Rosenfeld, MD
Experts debate the controversies surrounding the design and outcomes of the SAGhE cohort study.

Transitions of Care
Practice Resource | No credit available
Resources for you and your patients to facilitate the challenging transition from pediatric to adult endocrine practice. Topics include growth hormone deficiency, Turner syndrome, and type 1 diabetes.

Pediatric Endocrinology Digital Toolkit
Patient Resource | No credit available
Reviewer: Alicia Diaz-Thomas MD
Interactive and downloadable resources and information for patients and caregivers with questions related to children’s health and development including growth, puberty, and diabetes.

Pediatric Obesity: The Hidden High Costs of Junk Food
Patient Resource | No credit available
Interactive and downloadable infographic for patients and caregivers with questions about how children’s food choices can affect health and healthcare costs.

Bariatric Surgery and Adolescents
Patient Resource | No credit available
Interactive and downloadable infographic for caregivers with questions about bariatric surgery is an option for their child.

Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature
JCEM | October 6, 2016
Nelly Mauras, Judith L. Ross, Priscila Gagliardi, Y. Miles Yu, Jobayer Hossain, Joseph Permuy, Ligeia Damaso, Debbie Merinbaum, Ravinder J. Singh, Ximena Gaete, and Veronica Mericq
Context: Growth of short children in puberty is limited by the effect of estrogen on epiphyseal fusion. Objectives: To compare: 1) the efficacy and safety of aromatase inhibitors…

Cord Blood Adipokines and Lipids and Adolescent Nonalcoholic Fatty Liver Disease
JCEM | September 20, 2016
Joy Simpson, Andrew D. Smith, Abigail Fraser, Naveed Sattar, Mark Callaway, Robert S. Lindsay, Debbie A. Lawlor and Scott M. Nelson
Context: Maternal adiposity in pregnancy is associated with offspring adiposity and metabolic dysfunction postnatally, including greater risk of nonalcoholic fatty liver disease (NAFLD). Recent genetic…

Incidence, Prevalence, Diagnostic Delay, and Clinical Presentation of Female 46,XY Disorders of Sex Development
JCEM | September 7, 2016
Agnethe Berglund, Trine H. Johannsen, Kirstine Stochholm, Mette H. Viuff, Jens Fedder, Katharina M. Main and Claus H. Gravholt
Context: The prevalence of phenotypic females with a 46,XY karyotype is low, thus current knowledge about age and clinical presentation at diagnosis is sparse even…

Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ
JCEM | August 15, 2016
Adeline K. Nicholas, Eva G. Serra, Hakan Cangul, Saif Alyaarubi, Irfan Ullah, Erik Schoenmakers, Asma Deeb, Abdelhadi M. Habeb, Mohammad Almaghamsi, Catherine Peters, Nisha Nathwani, Zehra Aycan, Halil Saglam, Ece Bober, Mehul Dattani, Savitha Shenoy, Philip G. Murray, Amir Babiker, Ruben Willemsen, Ajay Thankamony, Greta Lyons, Rachael Irwin, Raja Padidela, Kavitha Tharian, Justin H. Davies, Vijith Puthi, Soo-Mi Park, Ahmed F. Massoud, John W. Gregory, Assunta Albanese, Evelien Pease-Gevers, Howard Martin, Kim Brugger, Eamonn R. Maher, V. Krishna K. Chatterjee, Carl A. Anderson and Nadia Schoenmakers
Context: Lower TSH screening cutoffs have doubled the ascertainment of congenital hypothyroidism (CH), particularly cases with a eutopically located gland-in-situ (GIS). Although mutations in known…

Features and Outcome of Autonomous Thyroid Nodules in Children: 31 Consecutive Patients Seen at a Single Center
JCEM | August 8, 2016
Samantha Ly, Mary C. Frates, Carol B. Benson, Hope E. Peters, Frederick D. Grant, Laura A. Drubach, Stephan D. Voss, Henry A. Feldman, Jessica R. Smith, Justine Barletta, Monica Hollowell, Edmund S. Cibas, Francis D. Moore Jr, Biren Modi, Robert C. Shamberger and Stephen A. Huang
Context: Most thyroid nodules are benign and their accurate identification can avoid unnecessary procedures. In adult patients, documentation of nodule autonomy is accepted as reassurance…

The Long-Term Outcome of Boys With Partial Androgen Insensitivity Syndrome and a Mutation in the Androgen Receptor Gene
JCEM | July 12, 2016
A. Lucas-Herald, S. Bertelloni, A. Juul, J. Bryce, J. Jiang, M. Rodie, R. Sinnott, M. Boroujerdi, M. Lindhardt Johansen, O. Hiort, P. M. Holterhus, M. Cools, G. Guaragna-Filho, G. Guerra-Junior, N. Weintrob, S. Hannema, S. Drop, T. Guran, F. Darendeliler, A. Nordenstrom, I. A. Hughes, C. Acerini, R. Tadokoro-Cuccaro and S. F. Ahmed
Background: In boys with suspected partial androgen insensitivity syndrome (PAIS), systematic evidence that supports the long-term prognostic value of identifying a mutation in the androgen receptor…

Testicular Growth during Puberty in Boys with and Without a History of Congenital Cryptorchidism
JCEM | April 6, 2016
Sergey Sadov, Jaakko J. Koskenniemi, Helena E. Virtanen, Antti Perheentupa, Jørgen H. Petersen, Niels E. Skakkebaek, Katharina M. Main and Jorma Toppari
Context: The pattern of testicular growth during puberty may provide important information about early testicular damage and reproductive potential in adulthood. Objective: To evaluate pubertal testicular…

Coming Up Short: Risks of Bias in Assessing Psychological Outcomes in Growth Hormone Therapy for Short Stature
JCEM | November 19, 2015
M. Gardner, M. L. Boshart, C. E. Yeguez, K. M. Desai and D. E. Sandberg
Context: Two often cited assumptions for treating children with GH are that short stature (SS), as an isolated physical characteristic, is associated with psychosocial morbidity…

Asfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia
JCEM | November 3, 2015
Michael P. Whyte, Cheryl Rockman-Greenberg, Keiichi Ozono, Richard Riese, Scott Moseley, Agustin Melian, David D. Thompson, Nicholas Bishop and Christine Hofmann
Context: Hypophosphatasia (HPP) is an inborn error of metabolism that, in its most severe perinatal and infantile forms, results in 50–100% mortality, typically from respiratory complications…

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency
JCEM | April 30, 2011
Phyllis W. Speiser, Ricardo Azziz, Laurence S. Baskin, Lucia Ghizzoni, Terry W. Hensle, Deborah P. Merke, Heino F. L. Meyer-Bahlburg, Walter L. Miller, Victor M. Montori, Sharon E. Oberfield, Martin Ritzen, and Perrin C. White
We recommend universal newborn screening for severe steroid 21-hydroxylase deficiency followed by confirmatory tests. We recommend that prenatal treatment of CAH continue to be regarded…

Endocrine Treatment of Transsexual Persons
JCEM | April 30, 2011
Wylie C. Hembree, Peggy Cohen-Kettenis, Henriette A. Delemarre-van de Waal, Louis J. Gooren, Walter J. Meyer, III, Norman P. Spack, Vin Tangpricha, and Victor M. Montori
Transsexual persons seeking to develop the physical characteristics of the desired gender require a safe, effective hormone regimen that will 1) suppress endogenous hormone secretion…

ENDO 2017 Preconference
Endocrine Fellows Series: Type 1 Diabetes Care and Management

Dates: March 29 - 30, 2017
Location: Orlando, Florida, United States
Sponsor: Endocrine Society

ENDO 2017 Preconference
3rd World Conference on Kisspeptin

Dates: March 30 - 31, 2017
Location: Orlando, Florida, United States
Sponsor: Kisspeptin Conference Organizers

8th International Conference on Children’s Bone Health
Dates: June 10 - 13, 2017
Location: Würzburg, Germany
Sponsor: ICCBH 

10th International Meeting of Pediatric Endocrinology
Dates: September 14 - 17, 2017
Location: Washington, DC, United States
Sponsor: Pediatric Endocrine Society

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