Pediatric endocrinologyDedicated to the Research and Treatment of Childhood Endocrine Disorders

Hear the latest news, learn about exciting research, and apply guidelines to stay at the leading edge of understanding and treating endocrine disorders, and bridging pediatric and adult care.

Children at High Risk of Diabetes Should be Screened by HbA1C and Oral Glucose Tolerance Tests
April 4, 2017 | Doctors should add an oral glucose tolerance test (OGTT) to their hemoglobin A1C (HbA1C) when they screen high-risk children for prediabetes and diabetes, new research…

Urine Metabolites May Help Predict Which Obese Teens Will Develop Diabetes
April 4, 2017 | Researchers have discovered a unique metabolic “signature” in the urine of diabetic, obese black teenagers that they say may become a way to predict the development of type 2 diabetes…

Vitamin D Deficiency May Indicate Cardiovascular Disease in Overweight and Obese Children
April 4, 2017 | In overweight and obese children and adolescents, vitamin D deficiency is associated with early markers of cardiovascular disease, a new study reports. The research…

In the US Military, White Kids and Officers' Kids More Likely to Use Diabetes Control Technology
April 3, 2017 | Even with equal access to healthcare in the United States military, significant disparities in caring for children with type 1 diabetes still exist…

Brain Signals After a Meal Respond to Food Pictures More in Obese Than Lean Kids
April 3, 2017 | Brain signals that should help tell us we are full after eating appear to be dulled in obese children, according to preliminary results of a new study presented Monday at ENDO 2017…

Artificial Pancreas Improves Blood Sugar Control in Young Kids
April 3, 2017 | An artificial pancreas, which delivers insulin in an automated way to individuals with type 1 diabetes, appears to be safe and effective for use in children ages 5 to 8…

Alcohol Abuse Even Before Pregnancy May Harm Offspring
April 2, 2017 | Mothers who binge drink before they become pregnant may be more likely to have children with high blood sugar and other changes in glucose function…

Easing the Burden of Childhood Obesity
March 2017 | According to the Endocrine Society’s Facts and Figures report on Obesity, 16.9% of U.S. children age 2 to 19 years are obese, having a body mass index (BMI) at or above the 95th percentile for age and sex…

Endocrine Society Experts Issue Clinical Practice Guideline on Pediatric Obesity
January 31, 2017 | The Endocrine Society today issued a Clinical Practice Guideline advising healthcare providers on how to prevent and treat childhood obesity with lifestyle changes...

Type 1 Diabetes Linked to Gut Inflammation, Gut Bacteria Changes
January 19, 2017 | People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria­—a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study published in JCEM...

Explore highlights of current education across the Endocrine Society.


Hypophosphatasia: New Options in the Management of Alkaline Phosphatase Deficiency
ENDO Satellite Symposium | 2.0 AMA PRA Category 1 Credits™ and ABIM MOC Part 2 points
Chair: Jill H. Simmons, MD
Faculty: Nancy S. Dunbar, MD, MPH; Peter J. Tebben, MD; and Michael P. Whyte, MD
What does low alkaline phosphatase mean in practice? Recognize subtle signs of HPP in pediatric and adult patients and learn about the most recent treatment approvals.

Transitions of Care
Practice Resource | No credit available
Resources for you and your patients to facilitate the challenging transition from pediatric to adult endocrine practice. Topics include growth hormone deficiency, Turner syndrome, and type 1 diabetes.

Pediatric Endocrinology Digital Toolkit
Patient Resource | No credit available
Reviewer: Alicia Diaz-Thomas MD
Interactive and downloadable resources and information for patients and caregivers with questions related to children’s health and development including growth, puberty, and diabetes.

Pediatric Obesity: The Hidden High Costs of Junk Food
Patient Resource | No credit available
Interactive and downloadable infographic for patients and caregivers with questions about how children’s food choices can affect health and healthcare costs.

Bariatric Surgery and Adolescents
Patient Resource | No credit available
Interactive and downloadable infographic for caregivers with questions about bariatric surgery is an option for their child.

Explore highlights of current publications across the Endocrine Society journals. Visit academic.oup.com/endocrinesociety for more.


Genetic Variation of Follicle-Stimulating Hormone Action is Associated with Age at Testicular Growth in Boys
JCEM | February 27, 2017
Alexander S. Busch, Casper P. Hagen, Katharina M. Main, Anita Pereira, Camila Corvalan, Kristian Almstrup, Veronica Mericq, and Anders Juul
Context: Although genetic factors play a pivotal role in male pubertal timing, genome-wide association…

GH Treatment in Children with Prader-Willi Syndrome: 3 Years Longitudinal Data in Prepubertal Children and Adult Height Data from KIGS Database
JCEM | February 16, 2017
N.E. Bakker, A. Lindberg, J. Heissler, H.A. Wollmann, C. Camacho-Hübner, and A.C. Hokken-Koelega on behalf of the KIGS Steering Committee
Context: Longitudinal data of children with Prader-Willi syndrome (PWS) treated with Genotropin were registered in Pfizer-…

Cancer Risks in Patients Treated with Growth Hormone in Childhood: The SAGhE European Cohort Study
JCEM | February 10, 2017
Anthony J Swerdlow, Rosie Cooke, Dominique Beckers, Birgit Borgström, Gary Butler, Jean-Claude Carel, Stefano Cianfarani, Peter Clayton, Joël Coste, Annalisa Deodati, Emmanuel Ecosse, Ruth Gausche, Claudio Giacomozzi, Anita CS. Hokken-Koelega, Aysha J Khan, Wieland Kiess, Claudia E. Kuehni, Primus-E. Mullis, Roland Pfaffle, Lars Sävendahl, Grit Sommer, Muriel Thomas, Anders Tidblad, Sally Tollerfield, Liesbet Van Eycken, and Gladys RJ. Zandwijken
Context: Growth Hormone (GH) is prescribed for an increasing range of indications, but there has been concern that it might raise cancer risk. Published data are limited…

Cord Blood Adipocyte Fatty Acid Binding Protein Levels Correlate With Gestational Age And Birth Weight In Neonates
JCEM | January 31, 2017
Kyoung Eun Joung, Sule Umit Cataltepe, Zoe Michael, Helen Christou, and Christos S. Mantzoros
Context: Infants born small for gestational age (SGA) have increased risk for obesity and metabolic syndrome in future life, but the underlying mechanisms…

Whole-exome Sequencing for Diagnosis of Turner Syndrome: Towards Next Generation Sequencing and Newborn Screening
JCEM | January 24, 2017
David R. Murdock, Frank X. Donovan, Settara C. Chandrasekharapp, Nicole Banks, Carolyn Bondy, Maximilian Muenke, and Paul Kruszka
Context: Turner syndrome (TS) is due to a complete or partial loss of an X chromosome in females and is not currently part of newborn screening…

Cardiorespiratory Fitness and Adiposity as Determinants of Metabolic Health – Pooled Analysis of Two Twin Cohorts
JCEM | January 23, 2017
Sakari Jukarainen, René Holst, Christine Dalgård, Päivi Piirilä, Jesper Lundbom, Antti Hakkarainen, Nina Lundbom, Aila Rissanen, Jaakko Kaprio, Kirsten Ohm Kyvik, Thorkild I.A. Sørensen, and Kirsi H. Pietiläinen
Context: The joint effects of cardiorespiratory fitness and body composition on metabolic health are not well known…

Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature
JCEM | October 6, 2016
Nelly Mauras, Judith L. Ross, Priscila Gagliardi, Y. Miles Yu, Jobayer Hossain, Joseph Permuy, Ligeia Damaso, Debbie Merinbaum, Ravinder J. Singh, Ximena Gaete, and Veronica Mericq
Context: Growth of short children in puberty is limited by the effect of estrogen on epiphyseal fusion. Objectives: To compare: 1) the efficacy and safety of aromatase inhibitors…

Cord Blood Adipokines and Lipids and Adolescent Nonalcoholic Fatty Liver Disease
JCEM | September 20, 2016
Joy Simpson, Andrew D. Smith, Abigail Fraser, Naveed Sattar, Mark Callaway, Robert S. Lindsay, Debbie A. Lawlor, and Scott M. Nelson
Context: Maternal adiposity in pregnancy is associated with offspring adiposity and metabolic dysfunction postnatally, including greater risk of nonalcoholic fatty liver disease (NAFLD). Recent genetic…

Incidence, Prevalence, Diagnostic Delay, and Clinical Presentation of Female 46,XY Disorders of Sex Development
JCEM | September 7, 2016
Agnethe Berglund, Trine H. Johannsen, Kirstine Stochholm, Mette H. Viuff, Jens Fedder, Katharina M. Main, and Claus H. Gravholt
Context: The prevalence of phenotypic females with a 46,XY karyotype is low, thus current knowledge about age and clinical presentation at diagnosis is sparse even…

A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study
JCEM | September 1, 2016
Fabio Lauria, Alfonso Siani, Catalina Picó, Wolfgang Ahrens, Karin Bammann, Stefaan De Henauw, Ronja Foraita, Licia Iacoviello, Yiannis Kourides, Staffan Marild, Denes Molnar, Luis A. Moreno, Yannis Pitsiladis, Juana Sánchez, Toomas Veidebaum, Guan Wang, and Paola Russo on behalf of the IDEFICS consortium
According to the recent World Health Organization report, the prevalence of childhood obesity increased at an alarming rate during the last decades in many countries. Although the increasing rates are apparently plateauing in some Western countries, it remains a serious challenge and a public health priority…

For a complete list of Endocrine Society guidelines, visit endocrine.org/guidelines.


Pediatric Obesity—Assessment, Treatment, and Prevention
JCEM | January 31, 2017
Dennis M. Styne, Silva A. Arslanian, Ellen L. Connor, Ismaa Sadaf Farooqi, M. Hassan Murad, Janet H. Silverstein, and Jack A. Yanovski
Pediatric obesity remains an ongoing serious international health concern affecting about 17% of United States children and adolescents, threatening their adult health…

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency
JCEM | April 30, 2011
Phyllis W. Speiser, Ricardo Azziz, Laurence S. Baskin, Lucia Ghizzoni, Terry W. Hensle, Deborah P. Merke, Heino F. L. Meyer-Bahlburg, Walter L. Miller, Victor M. Montori, Sharon E. Oberfield, Martin Ritzen, and Perrin C. White
We recommend universal newborn screening for severe steroid 21-hydroxylase deficiency followed by confirmatory tests. We recommend that prenatal treatment of CAH continue to be regarded…

Endocrine Treatment of Transsexual Persons
JCEM | April 30, 2011
Wylie C. Hembree, Peggy Cohen-Kettenis, Henriette A. Delemarre-van de Waal, Louis J. Gooren, Walter J. Meyer, III, Norman P. Spack, Vin Tangpricha, and Victor M. Montori
Transsexual persons seeking to develop the physical characteristics of the desired gender require a safe, effective hormone regimen that will 1) suppress endogenous hormone secretion…

For additional meetings, visit the Endocrine Society’s Worldwide Endocrinology Calendar at endocrine.org/calendar.


8th International Conference on Children’s Bone Health
Dates: June 10 - 13, 2017
Location: Würzburg, Germany
Sponsor: ICCBH 

10th International Meeting of Pediatric Endocrinology
Dates: September 14 - 17, 2017
Location: Washington, DC, United States
Sponsor: Pediatric Endocrine Society

Clinical Endocrinology Update & Endocrine Board Review
Dates: September 23–27, 2017
Location: Chicago, Illinois, United States
Sponsor: Endocrine Society
Whether you need the latest clinical information or you’re preparing to certify or recertify for the boards, Clinical Endocrinology Update (CEU) and Endocrine Board Review (EBR) have you covered.

ENDO Bridge
Dates: October 19–22, 2017
Location: Antalya, Turkey
Sponsor: Endocrine Society, the European Society of Endocrinology, and The Society of Endocrinology and Metabolism of Turkey
EndoBridge will provide a comprehensive update in the field of endocrinology for the clinical endocrinologist. The official language of the meeting is English, but simultaneous translation will be available in Russian, Arabic, and Turkish

ENDO 2018
Dates: March 17–20, 2018
Location: Chicago, Illinois, United States
Sponsor: Endocrine Society
ENDO is the world’s largest event for presenting and obtaining the latest in endocrine science and medicine with an extensive program covering a broad array of topics, various networking opportunities, poster sessions, updates on new products and technologies at the ENDOExpo, and more.

Resources