"The Endocrine Society appreciates the opportunity to comment on the Request for Information (RFI) on ways to reform the National Institutes of Health (NIH). Founded in 1916, the Endocrine Society is the world’s oldest, largest, and most active organization devoted to research on hormones and the clinical practice of endocrinology. Our membership of over 18,000 includes basic and clinical researchers supported by grants from the NIH who are making discoveries about human biology and translating those findings into new treatments and therapies for patients around the world. Our members participate on grant review panels, serve as mentors and educators for the next generation of biomedical researchers, and conduct research with industry partners. We affirm that NIH has a proven and longstanding record of success in delivering public health interventions that have improved the lives of citizens in the United States and around the world. In our comments, we identify several areas that the Committee could consider in efforts to improve NIH processes without destabilizing one of the world’s premier public health institutions."