- Advocacy in Action: NIH Funding, Physician Payment Changes, the EPA, and More...
- Heir on the Side of Caution: How a Von Hippel-Lindau Patient Is Managing Her Health–In the two decades since Stacy Lloyd was diagnosed with the Von Hippel-Lindau, much has changed in genetic research, treatment, and counseling methods.
- HSD3B1 Positively Regulated by Androgen Receptor Signaling in Prostate Cancer–The HSD3B1 gene is positively regulated by androgens and androgen receptors (ARs), a finding that may play a role in more tailored treatment of prostate cancer...
- Positive Top-Line Results Announced from the Pivotal Phase 3 SONICS Study of Levoketoconazole for the Treatment of Endogenous Cushing’s Syndrome
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We propose that Dio2 induction caused by SE accelerates production of T3 in different areas of the central nervous system and modifies the hippocampal gene expression profile, affecting the balance between adaptive and maladaptive mechanisms.
Reproductive Hormones and Subclinical Cardiovascular Disease in Midlife Women
Endogenous E1 levels were related to endothelial function and E2 to vascular remodeling, suggesting distinct roles of these estrogens. SHBG and FT have complex roles depending on the vessel under study.
Role of Thyroid Hormones in Skeletal Development and Bone Maintenance
The skeleton is an exquisitely sensitive and archetypal T3-target tissue that demonstrates the critical role for thyroid hormones during development, linear growth, and adult bone turnover and maintenance.
Update on Multiple Endocrine Neoplasia Type 2: Focus on Medullary Thyroid Carcinoma
The specific germline activating mutation of the RET proto-oncogene appears to be the first determinant of the age of MTC onset, but, presumably, different regulatory events determine long-term tumor behavior.