Ann E. Kearns, MD, PhD obtained her internal medicine training at the University of Chicago Hospitals, and her Endocrinology training at Massachusetts General Hospital. She joined the Mayo Clinic in Rochester, MN in 1998. She is currently the Chair of Quality and Safety in the Division of Endocrinology.

Dr. Kearns' research interests are the relationship between osteoporosis and cardiovascular disease, and the potential role of estrogen in the development of both diseases. She is involved in the Kronos Early Estrogen Prevention Study (KEEPS), which is a trial of hormone replacement early after the menopause and examines surrogate cardiovascular markers including coronary artery calcification, carotid intimal thickness, and vascular reactivity, in women randomized to placebo, oral, or transdermal therapies. Her study examines detailed bone density and biochemical markers of bone turnover in these women, with the goal of determining how cardiovascular disease and bone loss are affected by estrogen versus aging.

In addition, Dr. Kearns is interested in the optimal evaluation and treatment of patients following a hip fracture. This project involves population data in Olmsted County, MN to determine the risks for a second hip fracture and to help identify who best benefits from treatment after a hip fracture.