Journal of the Endocrine Society Journal Article

Global Rise of Compounded Weight-Loss Medicines

July 22, 2025

A Worrisome Trend

 

Nikhil Sood and Rohini Garg
Journal of the Endocrine Society, Volume 9, Issue 8, August 2025, bvaf084
https://doi.org/10.1210/jendso/bvaf084

Abstract

The rise of compounded weight-loss drugs has emerged as a pressing global health issue, threatening consumers and health-care systems. Factors fueling this crisis include the desire for rapid weight-loss options, inadequate regulatory frameworks, and the easy availability of compounded products through online platforms and social media. Vulnerable populations, particularly those searching for low-cost treatments, are hit hardest. Tackling this escalating problem calls for a comprehensive strategy: enhancing regulatory oversight, raising public awareness, and fostering stakeholder collaboration. We can reduce the health dangers of compounded weight-loss medications by addressing the underlying causes and improving consumer safety. This article examines the risks associated with compounded weight-loss drugs and suggests practical measures to protect public health.

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