Journal of the Endocrine Society Journal Article

Updated Approach to Antiobesity Pharmacotherapy

March 07, 2023
 

Connor Enright, Elizabeth Thomas, David R Saxon
Journal of the Endocrine Society, Volume 7, Issue 3, March 2023, bvac195
https://doi.org/10.1210/jendso/bvac195

Abstract

Despite professional society guidelines recommending that obesity be treated as a chronic disease by emphasizing the use of lifestyle modification in conjunction with pharmacotherapy, antiobesity medications are uncommonly prescribed in most clinical practices. The recent Food and Drug Administration approval of semaglutide 2.4 mg weekly to treat obesity — as well as other forthcoming advancements in diabetes and antiobesity medications — highlights the potential of pharmacotherapy to significantly augment weight loss efforts. In this Expert Endocrine Consult, we review the evolving role of antiobesity pharmacotherapy in clinical practice and suggest a framework for the use of these medications.

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