Thematic Issue Journals & Articles

Adrenal Disease 2021

October 07, 2021

an Endocrine Society Thematic Issue

 

Read our special collection of journal articles, published in 2020–2021, focused on adrenal disease! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designation.

In Endocrine Reviews, Claahsen and colleagues provide an authoritative review of the latest developments in congenital adrenal hyperplasia, incorporating new screening and genotyping approaches as well as clinical trial updates and results of long-term outcome studies. Rosenfield discusses normal and premature adrenarche, the maturational increase in androgen production the precedes puberty, focusing on new insights into the development of the zona reticularis. Nőlting and coauthors discuss the importance of ascertaining the specific genetic clusters involved in individual pheochromocytoma and paraganglioma cases, and suggest that genetic analysis should soon be able to guide management.

In Endocrinology, Lyu and colleagues report on a profound sexual dimorphism in the response of the prepubertal mouse zona fasciculata to thyroid hormone, a discovery that could shed light on why adrenal diseases are more common in females. Hill and Spencer-Segal discuss in a mini-review the role of exogenous and endogenous glucocorticoids in determining neuropsychiatric outcomes after critical illness. Valle and Sharifi evaluate prospects for combating the switch in glucocorticoid metabolism that can occur in metastatic prostate cancer and allow tumors to escape their reliance on androgen receptor signaling.

JCEM features a report by Li and coauthors that documents opioid-induced adrenal insufficiency in 9 percent of patients in a pain rehabilitation center. Vogel et al. report the persistence of muscle dysfunction in Cushing syndrome even after biochemical remission, and call for action to identify suitable interventions. Larsson and coauthors find, using the technique of Mendelian randomization, an association between plasma cortisol and atrial fibrillation. And Schernthaner-Reiter and colleagues document a wide spectrum of acute and life-threatening complications of Cushing syndrome, which includes ones prevalent before diagnosis and after successful surgery.

Javorsky and colleagues report in Journal of the Endocrine Society on serum cortisol cutoffs for diagnosis of adrenal insufficiency using newer specific cortisol assays. Ueland and coauthors report in the same journal that bedtime salivary cortisol measurement can be used as a screening test for Cushing syndrome in children. And Buonocore and colleagues report on 25 years’ experience of the genetic causes of primary adrenal insufficiency, finding that many cases have an identifiable genetic origin that is of value for management and that next-generation sequencing can often add value.

View this collection

Published: September 2021


About Endocrine Society Thematic Issues

It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.

Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.

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The Best of Endocrine Society Journals 2020

Explore a collection of top articles published in the Endocrine Society journals in 2020, selected on the basis of citations, downloads, and Altmetric score.

Explore a collection of top articles published in the Endocrine Society journals in 2020, selected on the basis of citations, downloads, and Altmetric score.

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