an Endocrine Society Thematic Issue
Read our special collection of journal articles focused on diabetes! These were published in 2019 and 2020, with curation guided by Altmetric Attention Score and Featured Article designation.
Galindo and colleagues discuss in Endocrine Reviews the challenges and emerging options for glycemic management of patients with diabetes and advanced chronic kidney disease. Lega and Lipscombe analyze the complex, bidirectional relationship between obesity, diabetes, and cancer, then consider clinical implications. Drucker reviews the basic and clinical science spanning the intersections of diabetes, coronavirus infections, and the biology of ACE2 and DPP4. Hirsch and coauthors discuss, as the 100th anniversary of the discovery of insulin approaches, how the biochemical properties of endogenous insulin have been modified to either shorten or extend the time-action profiles of injectable insulins.
In Endocrinology, Kolic and coauthors describe research on the effects of voclosporin and tacrolimus on human islets. The finding that the second, but not the first, inhibits insulin secretion could help explain increasing instances of new onset diabetes after transplant. Sangwung and colleagues review recent evidence that reduced mitochondrial function plays a critical role in insulin resistance, a fundamental component of type 2 diabetes, and ectopic lipid deposition. Fu and colleagues discuss the role of glucose-derived insulinotropic polypeptide in mediating hypothalamic inflammation and insulin resistance in diet-induced obesity.
In Journal of the Endocrine Society, Lin and colleagues describe evidence for the important effect of continuous glucose monitor alarm settings on hypo- and hyperglycemia outcomes; they propose optimal settings for avoidance of those conditions. Romeo and colleagues report results of a clinical trial of cinnamon supplements in people with prediabetes, finding benefits to fasting plasma glucose and glucose tolerance. Rees-Milton and coauthors find a link between statin use and insulin resistance in a comparison of 152 statin users and 457 non-users, even after correcting for propensity score. Barrera and colleagues, in a meta-analysis of patients with COVID-19, find that those with hypertension and diabetes have increased risk of admission to an intensive care unit and mortality, but not of severe COVID-19, compared to others.
In JCEM, Carmichael and associates find that improvements in glycemic control are associated with improvements in cognitive performance in older adults with type 2 diabetes who are being treated with intensive lifestyle intervention. Davis and colleagues document encouraging improvements in cardiovascular outcomes for people with type 2 diabetes since the 1990s, although the difference in all-cause mortality from that in people without diabetes has persisted. Bello-Chavolla and coauthors describe a lethality risk-score approach for use in first contact with patients diagnosed with COVID-19, one that includes diabetes, early-onset diabetes, and obesity, among other factors.
Published: November 2020
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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