an Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2021–2022, focused on obesity! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In Journal of the Endocrine Society, and coauthors report that in girls, higher weight gain during childhood predicts earlier puberty. Wabitsch and colleagues find that treatment with the melanocortin-4 receptor (MC4R) agonist setmelanotide reduced hunger and weight in patients with severe, early-onset obesity caused by specific gene variants that disrupt signaling via the MC4R. Andrisse and associates find that the racial and ethnic variation of metabolic syndrome components in girls with obesity and polycystic ovary syndrome (PCOS) match those of girls without PCOS.
In JCEM, Recalde et al. report that, in a population-based study, there was a monotonic association between body mass index and COVID-19 diagnosis and hospitalization risks, but a J-shaped relationship with mortality. Parente and colleagues find a positive correlation between waist-to-height ratio, a hallmark of central obesity, and severe diabetic eye disease in patients with type 1 diabetes mellitus. Sabag et al. report that high-intensity interval training is about as effective as moderate-intensity continuous training at reducing hepatic fat, which is considered a manifestation of metabolic syndrome.
In Endocrinology, Wasinski and associates report that growth hormone receptor-signaling in the brain is required for the orexigenic effect of ghrelin, independent of growth hormone action on a key subset of neurons in the arcuate nucleus of the hypothalamus. In a mini-review, Hoong and Chua discuss the action of sodium glucose cotransporter-2 inhibitors, concluding that the evidence is “compelling” that the drugs act as calorie-restriction mimetics in anti-aging therapeutics. In another mini-review, Klein and coauthors discuss the role of growth differentiation-factor 15, which reduces food intake and body weight when administered pharmacologically and is produced in larger amounts in the body during exercise.
In Endocrine Reviews, Manoogian et al. provide a treatise on time-restricted eating for the prevention and management of metabolic diseases. Angelidi and colleagues review the pathophysiology of energy homeostasis, highlighting pathways being explored in the effort to develop novel anti-obesity medications and interventions. And Howell and Booth analyze the evidence for relationships between the built environment, physical activity, and obesity-related diseases.
Published: June 2022
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
Join our endocrine community and become a member! Only members receive access to a variety of member benefits that will enhance your career. If your membership has lapsed, rejoin today so that you can continue to receive your membership benefits.
We provide our journal authors with a variety of resources for increasing the discoverability and citation of their published work. Use these tools and tips to broaden the impact of your article.