an Endocrine Society Thematic Issue
Read our special collection of journal articles, published in 2021–2022, focused on the thyroid! Curation of the collection was guided by Altmetric Attention Scores and Featured Article designations.
In Endocrinology, Liu and colleagues report an association between free thyroxine and both birth weight and birth weight discordance in twins. Brûlé and coauthors describe results with mice indicating that IGSF1 loss can impair production of thyroid-stimulating hormone independently of alterations in thyroid hormone-releasing hormone levels or thyroid hormone action. Halada and coauthors discuss hormonal crosstalk between thyroid cancer and breast cancer and its implications for future therapies.
In JCEM, Wu and associates report that subclinical hypothyroidism is associated with incident metabolic syndrome in young men. Ettleson et al. describe results suggesting suboptimal treatment of hypothyroidism is associated with worse hospital outcomes. And Krieger and colleagues used orbital fibroblasts from patients with thyroid eye disease to demonstrate a likely mechanism of action of teprotumumab.
In Journal of the Endocrine Society, Jurado-Flores and coauthors describe in a mini-review the pathophysiology of neuropsychiatric manifestations of thyroid disease, the understanding of which they suggest could help identify novel therapeutic targets for patients with neuropsychiatric disorders. Caetano et al. report that in a small group of patients with nonmedullary thyroid cancer, metformin caused a decrease in serum thyroglobulin, a surrogate marker for cancer burden. The effect was independent of levels of thyroid-stimulating hormone. Polavarapu and others find that use of Afirma’s Genomic Sequencing Classifier can lead to a lower rate of surgeries and a higher malignancy rate in patients who do have surgery for cytologically indeterminate thyroid nodules.
In Endocrine Reviews, Jonklaas discusses the subtleties of optimal thyroid hormone replacement, including the possible use of liothyronine in addition to levothyroxine. Andersson and Braegger review iodine nutrition and its association with thyroid function in lactating women, infants, and toddlers. And Van Iersel and associates describe recommendations for endocrine surveillance of childhood and young adult cancer survivors, who are at risk of developing malignancies as a result of toxic therapies; about 10 percent of these malignancies involve the thyroid.
Published: November 2022
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, and The Journal of Clinical Endocrinology & Metabolism, so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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