an Endocrine Society Thematic Issue
Read our special collection of journal articles focused on women’s health research! Curation of the collection, based on articles published in 2022 and 2023, was guided by Altmetric Attention Scores and Featured Article designations.
In Journal of the Endocrine Society, Anu Sharma and others report that lower serum total ceramide (16:0) and dihydrosphingomyelin concentrations are associated with a beneficial metabolic response to metformin in women with polycystic ovary syndrome (PCOS). Mayne and colleagues describe results supporting the utility of cortisol as a maternal serum biomarker for assessing the risk of preterm birth during early pregnancy. Salem et al. report that progesterone and progestins increase the uptake of labeled glucose in T47D breast cancer cells through the classical action of the progesterone receptor as a transcription factor.
In Endocrinology, Smith and colleagues provide evidence that vascular insulin resistance can be provoked by 10 days of reduced walking and consumption of sweetened beverages, and that this is associated with a decrease in serum adropin — although young women are protected. Tong and coauthors report that exposing a mouse breast cancer model to parabens at levels within the Food and Drug Administration’s “human acceptable daily intake” led to increased tumor volume and pulmonary metastasis; the chemicals impaired tumor RNA metabolism. Xi et al. describe how, in female rats, chronic psychological stress induced by a screaming sound sequentially decreased plasma anti-Müllerian hormone and estradiol concentrations, induced primordial and preantral follicle loss, augmented granulosa cell apoptosis in growing follicles, and eventually decreased litter sizes.
In JCEM, Hu and coauthors report that, in a study of women of reproductive age with obesity and PCOS, complete remission of PCOS after bariatric surgery was common but depended on the final body mass index achieved. Flachs Madsen and associates provide a systematic review of studies on long-term health outcomes in women diagnosed with gestational diabetes; the strongest association was with kidney disease, especially in Black women. Osinga et al. survey published reference intervals for thyrotropin and free thyroxine in pregnancy and find wide differences in methodology, but conclude that future studies could use a simpler process.
In Endocrine Reviews, Sweeting and coauthors provide a clinical update on gestational diabetes mellitus, concluding that it is a risk factor for type 2 diabetes and cardiovascular disease. Dapas and Dunaif offer a state-of-the-science review of genetic analyses of PCOS, along with an assessment of the contributions of environmental factors and developmental origins. And Gravholt et al. survey current understanding of Turner syndrome, emphasizing clinical advances and genomic insights.
Published: May 2023
It can be difficult to keep up to date in the rapidly evolving and expanding world of endocrine science. We curate topical collections of research from across our journals, Endocrine Reviews, Endocrinology, Journal of the Endocrine Society, The Journal of Clinical Endocrinology & Metabolism, and JCEM Case Reports so that you can easily find and read recent, influential articles on the topics that interest you.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.
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