Join researchers from around the world in Málaga, Spain, this September to learn the latest advancements in nuclear receptor research at our Science Summit 2026, Networked for Life: Nuclear Receptors in Age-related Diseases.
When: Monday, September 21 to Wednesday, September 23
Where: Málaga, Spain.
Who: The meeting will be chaired by Inés Pineda-Torra, CABIMER and Mercedes Ricote, CNB-CSIC with assistance from organizing committee members, Christopher Glass, UCSD, MD, PhD, and Donald McDonnell, PhD.
Presented by the Endocrine Society, the Science Summit is designed to showcase the latest advancements in nuclear receptor research, spanning from fundamental mechanisms to clinical applications in age-related diseases. This critical platform is for researchers from diverse disciplines to share insights on the fundamental properties of these versatile transcription factors in an international environment.
Schedule at a Glance
Science Summit 2026: Networked for Life: Nuclear Receptors in Age-related Diseases
21 September 2026
15:00-15:45 Registration
15:45 Opening Remarks by Science Summit Planning Committee
Inés Pineda-Torra, PhD: Distinguished Principal Investigator, CABIMER, Seville, Spain; Honorary Professor of Cardiometabolic Medicine, University College London, London, UK
Mercedes Ricote, PhD: Associate Professor, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain
Donald P. McDonnell, PhD: Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, Duke Cancer Institute and Duke University School of Medicine, Durham, NC
Christopher K. Glass, MD, PhD: Professor and Director, Green Center for Reproductive Biology Sciences, UT Southwestern Medical Center, Dallas, TX
16:00-17:30 “From Signal to Action: The Molecular Dialogue in Women’s Hormone Regulation”
“Advances in Targeting Nuclear Receptors for Cancer Treatment- Obesity Related Breast Cancer”
Myles A. Brown, MD: Director of the Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute; Professor of Medicine, Harvard Medical School, Boston, MA
“Molecular and Genomic Mechanisms of Estrogen Signaling, Enhancer Formation, and Gene Regulation”
W. Lee Kraus, PhD: Professor and Director, Green Center for Reproductive Biology Sciences, UT Southwestern Medical Center, Dallas, TX
“Progesterone Signalling in Action”
Carol A. Lange, PhD: Professor of Medicine and Pharmacology; Associate Director for Basic Science, Masonic Cancer Center, University of Minnesota, Minneapolis, MN
“The Mother of Metabolism - ESR1 in the Control of Mitochondrial Form and Function”
Andrea L. Hevener, PhD: Professor of Medicine, Division of Endocrinology, Diabetes and Hypertension, University of California, Los Angeles, Los Angeles, CA
“Nuclear Receptor Crosstalk in Metabolic Control”
Karolien De Bosscher, PhD: Professor, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium
“Using Regulators of Cholesterol Homeostasis to Shift Tumour Immunology”
Erik R. Nelson, PhD: Professor of Molecular & Integrative Physiology; Keith W. and Sara M. Kelley Endowed Professor of Immunophysiology, University of Illinois Urbana-Champaign, Urbana, IL
11:00-11:30 Coffee break & Networking
11:30-13:00 “Molecular Switches, Major Impacts: Decoding Hormone Regulation in Immunomodulation”
“Arterial Protection by Estrogens: A Matter of Age?”
Coralie Fontaine, PhD: Research Director, Inserm; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Toulouse, France
“The LXR-CD38 axis in Inflammation and Metabolism”
Annabel Valledor, PhD: Associate Professor, Department of Cell Biology, Physiology and Immunology, University of Barcelona, Barcelona, Spain
“Glucocorticoid activation of anti-inflammatory macrophages protects against insulin resistance”
Jan Tuckermann, PhD: Professor and Director, Institute of Molecular Endocrinology and Physiology, Ulm University, Ulm, Germany
13:00-14:30 Lunch and Networking
14:30-15:15 Bright Sparks Session II
15:15-17:00 Poster Session I & Network
17:00- 19:00 “Next-Gen Hormone Networks: Insights on Age-Related Diseases”
Nuclear Receptor Epigenomics in Cancer; From Trials to Mechanisms and Back Again”
Wilbert Zwart, PhD: Senior Group Leader, Division of Oncogenomics, The Netherlands Cancer Institute (NKI); Professor of Functional Genomics in Oncology, Eindhoven University of Technology, Amsterdam, The Netherlands
“The Role of Nuclear Receptors and Pioneer Factors in Cancer Metastasis”
Jason S. Carroll, PhD: Professor of Molecular Oncology, University of Cambridge; Senior Group Leader, Cancer Research UK Cambridge Institute, Cambridge, UK
Delphine Duteil, PhD: Inserm Researcher, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, Strasbourg, France
“Hepatic Nuclear Receptor Circuitries Governing Homeostasis and Pathogenesis”
Henriette Uhlenhaut, PhD: W3 Professor and Chair for Metabolic Programming, TUM School of Life Sciences, Technical University of Munich (TUM); Director, Institute for Diabetes and Endocrinology, Helmholtz Munich, Munich, Germany
23 September 2026
9:00-11:00 “Orphans & Adopted: The Not so New Kids on Block”
“Nur77 is Orphan but not Lonely”
Caroline J.M. de Vries, PhD: Professor of Medical Cell Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
“PPARgamma and adipose tissue plasticity”
Susanne Mandrup, PhD: Professor, Department of Biochemistry and Molecular Biology; Director of the Center of Excellence in Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark
“Circadian Regulation of Organismal Metabolism By REV-ERB Nuclear Receptors”
Mitchell A. Lazar, MD, PhD: Willard and Rhoda Ware Professor in Diabetes and Metabolic Diseases; Director of the Penn Diabetes Research Center and Founding Director of the Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, PA
“PPARalpha Regulates Hepatic Proteostasis”
David D. Moore, PhD: Professor, Nutritional Sciences and Toxicology, Department of Metabolic Biology & Nutrition, University of California, Berkeley, Berkeley, CA
11:00-11:30 Coffee break
11:30-12:30 “Inflammation Reloaded: Nuclear Receptors at the Crossroads of Inflammation and Resolution”
“Transcriptional and Epigenomic Programming of Macrophages”
Inez Rogatsky, MSc, PhD: Professor of Microbiology and Immunology, Weill Cornell Medicine; Senior Scientist, Hospital for Special Surgery, New York, NY
“NR5A2/LRH-1 in Immune Tolerization and Wound Healing Resolution”
Benoit R. Gauthier, PhD: Principal Investigator, Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), Seville, Spain
12:30-13:00 Bright Sparks Session III
13:00-14:00 Lunch and Networking
14:00-16:00 Poster Session II and Networking Break
16:00-18:00 “The Endocrine Revolution: Novel Therapeutic Approaches”
“PPAR Discovery Pipelines"
Robert Sims, PhD: Chief Scientific Officer and Co-Founder, Flare Therapeutics, Cambridge, MA
“THRb in MASH and Liver Fibrosis”
Rebecca Taub, MD: Founder, Board Director, and Senior Scientific and Medical Advisor, Madrigal Pharmaceuticals, Conshohocken, PA
“The Multimerization Pathways of the Androgen and Glucocorticoid Receptors Reveal Novel Druggable Sites”
Eva Estébanez-Perpiñá, PhD: Associate Professor and Research Group Leader, Department of Biochemistry and Molecular Biomedicine, University of Barcelona, Barcelona, Spain
“Nuclear Receptor Targeting in Prostate Cancer: Challenges and Opportunities”
Scott M. Dehm, PhD: Professor, Apogee Enterprises Professorship in Cancer Research, Masonic Cancer Center and the Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN
18:00-19:30 Special Topic Roundtable:
“The New Wave: Charting the Course for Future Nuclear Receptor Discovery”
This session will explore emerging trends and future directions in nuclear receptor research.
All speakers
20:30 Gala Dinner
Scope & Topics
The Summit is designed to foster dynamic discussion and networking through a comprehensive program of interactive activities. The relaxed environment will foster in-depth scientific exchange and provide an informal setting — particularly valuable for trainees and early-career researchers — to engage directly with invited speakers on the following primary topics and related sessions:
From Signal to Action: The Molecular Dialogue in Women’s Hormone Regulation
Next-Gen Hormone Networks: Insights on Age-Related Diseases
Inflammation Reloaded: Nuclear Receptors at the Crossroads of Inflammation and Resolution
The New Wave: Charting the Course for Future Nuclear Receptor Discovery
Audience
Early-career researchers and trainees, as well as established academic and industry scientist will engage in vibrant discussion and networking among participants through a comprehensive program of engaging activities.
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The Endocrine Society Calendar offers a list of upcoming domestic and international endocrinology events in one convenient place. Be sure to check back periodically for new member-exclusive webinars, Society events, future meetings, and more.
The Endocrine Society Calendar offers a list of upcoming domestic and international endocrinology events in one convenient place. Be sure to check back periodically for new member-exclusive webinars, Society events, future meetings, and more.
