Podcast Endocrine News

Clinical Practice Guideline on Central Precocious Puberty

June 25, 2026

EPN113

The Endocrine Society recently released a new Clinical Practice Guideline (CPG) on Central Precocious Puberty. Among its many recommendations, the CPG says some subgroups of children with precocious puberty—such as older girls with slowly progressing puberty—may not need the same level of testing or treatment.

Central precocious puberty happens when a child’s brain activates puberty-related hormones too early—before age 8 years in girls and before age 9 years in boys. This early hormone signaling triggers physical changes such as breast development in girls, testicular enlargement in boys, rapid growth, and, in some cases, early menstruation.

Host Aaron Lohr talks with authors of the CPG on Central Precocious Puberty: Ana Latronico, MD, PhD, Professor of Endocrinology and Metabolism at Sao Paolo University and Stephanie Roberts, MD, pediatric endocrinologist and Assistant Professor of Pediatrics at Boston Children's Hospital. 

 


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