Clinically relevant articles examine the effect of statins and biguanides on neuroendocrine tumors and the response to treatment of neuroendocrine tumors with 177Lu-DOTATATE. Additional articles explore the neuroendocrine mechanisms underlying functional hypogonadotropic hypogonadism (FHH) in men, describe a blood mRNA test for neuroendocrine tumor diagnosis, and investigate the incidence of cancer in patients with acromegaly.
Basic science articles demonstrate that gonadotropin-releasing hormone (GnRH) receptor-expression is necessary for reproductive function, suggest that free fatty acids suppress gonadotropins, and explore whether cats are a useful model for studying acromegaly. Review articles discuss the role of serotonin in regulating metabolism and the genetic and epigenetic changes implicated in gastroenteropancreatic neuroendocrine tumors.
Selection in each Thematic Issue is guided by online metrics, including Altmetric Attention Scores, Featured Article designations, and identification of leading authors and key topics. Each month, we publish a new Thematic Issue online and work to highlight and promote endocrine science in the press, through email, on social media and across other distribution channels.