Podcast Journal Club

Diagnosing Adrenal Insufficiency

July 24, 2025

EFL063

For our 63rd episode, we returned to the Endocrine Society’s annual meeting and recorded before a live audience at ENDO 2025 in San Francisco. We look at a study from The Journal of Clinical Endocrinology & Metabolism that suggests that we can substantially alter our diagnostic approach to adrenal insufficiency. This study and others have already led to a shift in recommendations from some experts, so we thought it would be of great interest to you all as our listeners. Host Chase Hendrickson, MD, from Vanderbilt University talks with regular contributor Katie Guttenberg, MD, from the University of Texas Health Science Center at Houston, and guest expert Anand Vaidya, MD, from Brigham and Women’s Hospital and Harvard Medical School in Boston.

live recording of Endocrine Feedback Loop podcast episode 63

They discuss “Performance of Dehydroepiandrosterone Sulfate and Baseline Cortisol in Assessing Adrenal Insufficiency” by Han et al, first published online in JCEM in December 2024.

Meet the Speakers

Anand Vaidya and Katie Guttenberg

Anand Vaidya, MD, is the director of the Center for Adrenal Disorders and interim chief of the Division of Endocrinology, Diabetes, and Hypertension at Brigham and Women’s Hospital, as well as an associate professor of medicine at Harvard Medical School. He leads a translational research laboratory that conducts human physiology studies, mechanistic clinical trials, and population-based studies focused on investigating the role the adrenal glands in health and disease. Dr. Vaidya directs the Interactive Medical Case series for The New England Journal of Medicine, created and directed the pre-clerkship endocrinology curriculum for Harvard medical students in the pathways curriculum, and routinely teaches practicing clinicians and trainees about adrenal physiology and disease.

Katie Guttenberg, MD, is an associate professor of medicine at McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston), where she is the program director for the endocrinology fellowship program. She received her medical degree from the Perelman School of Medicine at the University of Pennsylvania and completed her medical residency, fellowship in endocrinology, and fellowship in medical education at the University of Pennsylvania. Dr. Guttenberg received the McGovern Medical School at UTHealth Smythe Award for Excellence in Resident Education. Her clinical practice focuses on pituitary disorders.

We have four senior fellows joining us to help analyze the article. They each submitted questions in advance, and we called on them throughout the episode to ask those questions. Those fellows are Natalia Fretes Oviedo, MD, from the Cleveland Clinic; Nikola Gligorijevic, MD, from the University of Pittsburgh; Rinki Pandya, MD, from Oregon Health & Science University; and Aye Khine, MD, from University of California, San Francisco.


Meet the Host

Chase HendricksonChase Hendrickson, MD, MPH, practices general endocrinology at the Vanderbilt University Medical Center, where he is an associate program director for the endocrinology fellowship program. His interests include endocrine education, teaching inferential methods, and quality improvement.


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