JCEM Case Reports Journal Article

Lithium Monotherapy in Graves Thyrotoxicosis

September 05, 2023
 

James Larkworthy, Omar Kirresh, Ali Chakera, Fahad Ahmed
JCEM Case Reports, Volume 1, Issue 4, July 2023, luad094
https://doi.org/10.1210/jcemcr/luad094

Abstract

Lithium is not commonly used to treat thyrotoxicosis, and there are few reports in the literature of its use as initial therapy in thyrotoxicosis. We describe the case of a patient with Graves thyrotoxicosis and ophthalmopathy, on a background of autoimmune neutropenia, treated successfully with relatively long-term lithium monotherapy. Lithium was used at a lower dose and longer duration than previously reported on, to good effect. We demonstrate that lithium is an important and useful option for those who are unable to tolerate thionamide therapy.

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