Patients' Knowledge and Opinions Regarding Osteoporosis, Osteoporotic Treatments and Oral Health

Presentation Number: SAT-472-LB
Date of Presentation: March 17, 2018, 2018

Pnina Rotman-Pikielny, MD1, Marina Leonenko, RN2, Liat Barzilai, MD1, Dan Nabriski, MD1, Orit Twito, MD1, Ronit Kagan, DMD3.
1Endocrine Institute MEIR MED CTR affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Kfar-Saba, Israel, 2Department of Nursing Management, MEIR MED CTR affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Kfar-Saba, Israel, 3Oral and maxillofacial Surgery Unit MEIR MED CTR affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Kfar-Saba, Israel.


Objective: Osteonecrosis of the jaw is a rare side effect of antiresorptive treatment for osteoporosis, occurring in <0.001% of patients, especially those undergoing invasive dental procedures. Despite lack of conclusive evidence, professional societies recommend suspending antiresorptive treatment before invasive dental procedures. Lack of knowledge/misbeliefs might lead patients to discontinue antiresorptive treatment prematurely or avoid necessary dental procedures. This study assessed patients' knowledge and opinions regarding the association between osteoporosis, osteoporosis treatments and oral health. Material and Methods: In this observational study, conducted in Israel, outpatients with osteopenia/osteoporosis completed questionnaires, including socio-demographics, internet use, osteoporosis and oral hygiene status, and knowledge regarding the effect of osteoporosis and osteoporotic treatments on oral health and procedures. Results: Among 259 patients (68.5±9.3 years, 93% female), 66.5% had >12 years of education, 62.5% were native Hebrew speakers and 53.7% were exposed to the internet daily. 83.9% had osteoporosis, one-third had a previous osteoporotic fracture and 71.5% were on antiresorptives, including oral bisphosphonates, zoledronic acid and denosumab. 79.9% saw a dentist during the last year and 29.0% had an invasive dental procedure. Yet, 70% of the dentists did not inquire about the type or duration of osteoporosis treatment. Participants had minimal knowledge regarding associations among osteoporosis, its pharmacotherapy and oral health: 57% thought osteoporosis had no long-term complications, one-third thought it could damage existing crowns or implants and 70% it might increase gum disease. 70% thought one should stop osteoporosis treatment before having an implant, and 30% before cavity repair. 60% acquired information from professional staff and 90% wanted to learn more about the subject. Conclusions: Outpatients with osteoporosis and osteopenia have minimal knowledge about associations between osteoporosis, osteoporotic treatments and oral health. The medical community should provide balanced, accurate information to help patients prioritize healthcare and avoid unnecessary osteoporosis treatment interruptions.*Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. The Endocrine Society reserves the right to lift the embargo on specific abstracts that are selected for promotion prior to or during ENDO.


 P. Rotman-Pikielny: None. M. Leonenko: None. L. Barzilai: None. D. Nabriski: None. O. Twito: None. R. Kagan: None.