15th Annual Levine-Riggs Diabetes Research Symposium


Lipodystrophy Connect: The Global Registry
Elif A Oral, David Araujo-Vilar, Kyle Brown, Rebecca J. Brown, Abhimanyu Garg, Taisia Isupov, Deborah HP Jae, Vanessa Rangel Miller, David B Savage and Andra Stratton


Emerging Role of Serum IGF-I/IGFBP-3 Ratio in the Diagnosis of Children with Growth Hormone Deficiency
Ayman A. Zayed, Mohammad A. Zmaili, Marwa M. Sabha, Mohannad M. Saleh, Moaath K. Mustafa Ali, Aref L. Zayed, Suleiman I. Al Ashi, Al-Motassem Yousef and Hussein D. Abdul-latif


Circulating Levels of Acyl Ghrelin and Desacyl Ghrelin in Obese Individuals
Leon S Farhy, Jianhua Liu, Suzan S Pezzoli, Bruce D Gaylinn and Ralf Manfred Nass


Using Systems Approach to Identify Novel Genes Involved in High-Fat Diet Response in Mice Liver
Juan Du, Amy Leung, Candi Trac, Liang Zhou, Brian W. Parks, Aldons J Lusis, Rama Natarajan and Dustin E. Schones



Standardized Rat and Human Pancreatic Microislets for Diabetes Research and Drug Safety Assessment
Wolfgang Moritz, Irina Agarkova, Richard Prazak, Simon Messner, Roger Lehmann and Jens Kelm


Nucleobindin-1 (NUCB1) Encodes an Insulinotropic Nesfatin-1-like Peptide
Naresh Ramesh, Haneesha Mohan and Suraj Unniappan


Chrebp Mediated Hepatic Pander Expression
Whitney Ratliff and Brant R Burkhardt


Insulin Drip in Euglycemic Ketoacidosis - a Tough Nut to Crack!
Nilma Malik, Mohammad Islam, Reema A Patel and Abdalla Yousif


The Impact of Sleep Debt on Adiposity and Insulin Sensitivity in Patients with Early Diabetes
Shahrad Taheri, Teresa Arora, Ashley R Cooper, Robert Charles Andrews and Mimi Z Chen


Methylation-Specific PCR Assay for Detection of Beta Cell Death in Newly Onset Type 1 Diabetes
Mohamed I. Husseiny Elsayed, Leah Selby, Alexander Kaye, Eba Hathout, Fouad R Kandeel and Kevin George Ferreri


Glucagon-like Peptide-1 (GLP-1) Action on the Reproductive Neuroendocrine Axis
Kristy M. Heppner, Arian F. Baquero, Camdin Bennett, Melissa A. Kirigiti, Sarah R. Lindsley, Martha A. Bosch, Oline K. Ronnekleiv, Kevin L. Grove and M. Susan Smith


NFAT Stimulates Beta-Cell Proliferation and Insulin Secretion in Human and Mouse Islets
Mark P Keller, Pradyut K Paul, Mary E Rabaglia, Donnie S Stapleton, Jose Rodriguez-Martinez, Ning Leng, Christopher L Plaisier, Melkam A Kabede, Mark A Klein, Nitin S Baliga, Brian S Yandell, Christina Kendziorski, Aseem Z Ansari and Alan D Attie


Urocortin3 Triggers Somatostatin-Mediated Negative Feedback to Control Insulin Secretion
Talitha van der Meulen, Cynthia J. Donaldson, Anna Hunter, Elena L. Caceres and Mark O Huising


Mechanism of Omega-3 Fatty Acid Receptor, GPR120 Signaling in Insulin Resistance
Da Young OH, Evelyn Walenta, Vivian A Paschoal and Armen Abagyan


Acute Weight Loss Stimulates Lipolysis and Macrophage Infiltration in the Subcutaneous Adipose Tissue of Obese Women
José Orlando Alemán, Neil M Iyengar, Jeanne Walker, Juana Gonzalez, Ginger L Milne, Dilip D Giri, Clifford A Hudis, Jan L Breslow, Peter R Holt and Andrew J Dannenberg


Metformin Increases in Vivo 11ßHSD1 Activity in Obese Men with and without Type 2 Diabetes Mellitus
Anna J Anderson, Ruth Andrew, Natalie Z Homer, Gregory Jones, Kenneth Smith, Dawn EW Livingstone, Brian R Walker and Roland H Stimson


An Approved Drug Induces a Beta-like Phenotype in Alpha Cells
Jin Li, Kilian Huber, Thomas Frogne, Charles-Hugues Lardeau, Giulio Superti-Furga, Jacob Hecksher-Sorensen and Stefan Kubicek


Quinine Induces Adipogenesis in 3T3-L1 Preadipocytes
Sebastian D Parlee, Becky R Simon, Xiaomin Ning, Corinne Weinsheit and Ormond A MacDougald


Substantial Reduction in Length of Hospital Stay of Patients with Diabetic Ketoacidosis after Implementation of Clinical Practice Guidelines at a University Hospital in Saudi Arabia
Sarar Mohamed, Hala Omer, Amir Babiker, Hessah Al Otaibi, Shaikh Mohamed Iqbal, Mohamed Elfaki Osman, Ayman Al-Eyadhy, Mohamed Al-Othman, Abdulrahman Al Nemri, Yasser Sami Amer, Lubna Alansary, Khalid Alswat, Fahad Al-Zamil and Nasir Al-Juryyan


The Nuclear Receptor Signaling Atlas (NURSA): A Web Resource for the Nuclear Receptor Signaling Community
Neil McKenna, Lauren Becnel, Yolanda Darlington and Scott Andrew Ochsner


Prostaglandin E2 Levels As a Predictor of Disease Status in Human Subjects with Type 2 Diabetes Mellitus
Alicia Christine Weeks, Melanie Dart, Xhanhai Li, Dawn Belt Davis and Michelle E. Kimple



Heterogeneity and Lobularity during the Pre-Diabetic Phase: A Case Study
Teresa Rodriguez-Calvo, Jessica Suwandi, Natalie Amirian, Florence Anquetil, Somayeh Sabouri and Matthias von Herrath


Successful Vaccination of Hepatitis B Is Associated with a Better Metabolic Profile
Jean Huang, Horng-Yih Ou, James Lin, Rudruidee Karnchanasorn, Wei Feng, Raynald Samoa, Lee-Ming Chuang and Ken C Chiu


Renal Sympathetic Denervation Improves Metabolic Function in Obese Insulin Resistant Canines
Malini S Iyer, Orison O Woolcott, Viorica Ionut, Morvarid Kabir, Richard N Bergman and Cathryn Kolka


Epigenome-Wide Screen for Alpha to Beta Cell Transdifferentiation
Tamara Casteels, Jin Li and Stefan Kubicek


Adult Human Exocrine Pancreas Contains Multi-Potent Progenitor-like Cells That Form Colonies in a 3D Culture
Lena Wedeken, Tao Feng, Ismail H. Al-Abdullah, Fouad R Kandeel and Hsun Teresa Ku


The Effect of All Trans Retinoic Acid on Insulitis and Beta Cell Apoptosis in NOD Mice
Sana Hasan, Courtney Smith, Ronda White, Frederick G Hamel, Cyrus V Desouza and Robert G. Bennett


Are Families of Children with Type 1 DM Ready for Televisits?
Sena Cantas Orsdemir, Rebecca Feinberg, Holley F Allen and Ksenia N Tonyushkina


Waist Height Ratio As a Marker of Obesity and Insulin Resistance in Adolescents
V. Sri Nagesh, Rakesh Kumar Sahay, Neelaveni Kudugunti, Vishnu Vardhan Rao.M, Aditya Vikram B, Sridhar Bathula, Syed Mustafa Hashmi, Sana Hyder, Sania Jiwani and Hari Mohan R


Is a Calorie a Calorie? Metabolic Fat Balance Following Selective Isocaloric Restriction of Dietary Carbohydrate Vs. Fat in Obese Adults
Kevin D. Hall, Thomas Bemis, Robert J Brychta, Kong Chen, Amber B Courville, Stephanie Goodwin, Juen Guo, Lilian Howard, Nicolas D Knuth, Bernard V Miller III, Carla M Prado, Emma Preuschl, Mario Siervo, Monica C. Skarulis and Laura Yannai


Genome-Wide Gene Expression and DNA Methylation Profiles in Adipose Tissue from Women with and without PCOS
Milana Kokosar, Anna Benrick, Alexander Perfilyev, Emma Nilsson, Manuel Maliqueo, Carl Johan Behre, Antonina Sazonova, Charlotte Ling and Elisabet Stener-Victorin


Monogenic Diabetes and Targeted Next-Generation Sequencing in the Mody Registry Cohort of Poland
Magdalena Szopa, Agnieszka ludwig-Galezowska, Julita Machlowska, Jan Skupien, Piotr Radkowski, Tomasz Klupa, Beata kiec-Wilk, Iwona Wybranska, Pawel Wolkow and Maciej Malecki


Oral Immunotherapy for Type 1 Diabetes Based on Live Attenuated Salmonella
Mohamed I. Husseiny Elsayed, Weiting Du, Ding Wang, Jeffrey Rawson, Alexander Kaye, Fouad R Kandeel and Kevin George Ferreri


Induction of Mixed Chimerism for Cure of Overt Type 1 Diabetes in NOD Mice, Using Clinically Available Reagents without Radiation
Mingfeng Zhang, Qing Lin, Limin Wu, Nainong Li, Jeremy Racine, Qi Tong and Defu Zeng


Role of COH-SR4 in Diabetes: Glutathione-Linked Enzymes and Oxidative Stress
Sharad S Singhal, James L Figarola, Jyotsana Singhal, Samuel Rahbar and David Horne


Intracellular Calcium Leak Via RyR2 Induces ER Stress and Impairs Mitochondrial Fitness in Pancreatic Beta Cells Leading to Glucose Intolerance
Gaetano Santulli, Gennaro Pagano, Celestino Sardu, Steven Ross Reiken, Michele Cannone, Salvatore D Ascia, Nicola Marziliano, Bruno Trimarco, Theresa Ann Guise, Alain Lacampagne and Andrew Marks