New Mechanisms in Bone Biology: From Cells to Genetics, & Mice to Men


A RANKL-PKCβ-TFEB Signaling Cascade is Necessary for Lysosomal Biogenesis in Differentiated Osteoclasts
Mathieu Ferron, Carmine Settembre, Junko Shimazu, Julie Lacombe, Andrea Ballabio and Gerard Karsenty


Upregulation of type I collagen genes in osteogenesis imperfecta patients
Lilia Freire Rodrigues D'Souza-Li, Marcus Vinicius Pedroni, Marcelo Ananias Teocchi, Javier Adur, Ana Erika Dias Ferreira, Carlos L. Cesar and Carlos E. Steiner


The first Italian series of patients with Progressive Osseous Heteroplasia: screening for GNAS locus genetic and epigenetic defects
Francesca Marta Elli, Annamaria Barbieri, Paolo Bordogna, Elena Giardino, Emanuele Ferrante, Paolo Beck-Peccoz, Anna Spada and Giovanna Mantovani


Deletion of the cell-adhesion mediator PODXL in early osteoclast precursors impairs osteoclast resorption and causes osteopetrosis in female mice
Megan M Weivoda, Muzaffer Cicek, Ashok Kumar, Ming Ruan, Larry Pederson, Christine Hachfeld, Rachel Ann Davey, Michael Hughes, Kelly McNagny and Merry Jo Oursler


The Sirtuin 1 Activator SRTAW04 Restores Bone Mass and Structure in Ovariectomized Mice – A Potential Novel Therapy for Osteoporosis
Einav Cohen-Kfir, Hanna Artsi, Alon Bajayo, Yankel Gabet, Irina Gurt, Noga Kalish, Ron Shahar and Rivka Dresner-Pollak