Novel Mechanism of Glucocorticoid Metabolism and Action


11β-HSD1 Is the Major Regulator of the Tissue-Specific Effects of Circulating Glucocorticoid Excess
Stuart Andrew Morgan, Emma Louise McCabe, Laura Louise Gathercole, Zaki K Hassan-Smith, Dean Paul Larner, Iwona Bujalska, Paul M Stewart, Jeremy W Tomlinson and Gareth Geoffrey Lavery


A Glucocorticoid Receptor Haplotype That Enhances Glucocorticoid Sensitivity Is Associated with Increased Risk of Metabolic Syndrome: The Lifelines Cohort Study
Vincent L. Wester, Jan W. Koper, Erica L.T. van den Akker, Salome Scholtens, Ronald P. Stolk and Elisabeth F.C. van Rossum


Glucocorticoid Activation in Muscle By 11 ß-Hydroxysteroid Dehydrogenase Type 1: Contributions to Inflammatory Muscle Wasting
Rowan Samuel Hardy, Mark Pierson, Craig L Doig, Janet M Lord, Paul M Stewart, Gareth Geoffrey Lavery, Mark Stuart Cooper and Karim Raza


Glucocorticoid Receptor Isoform Knock-in Mice Have Unique Responses to Glucocorticoids
Sivapriya Ramamoorthy, Robert H Oakley, Julie F Foley and John A Cidlowski


The Interaction of MR and GR in the Nucleus and at DNA: Transcriptional Implications for the Glucocorticoid Response of Stress-Associated Brain Regions
John R Pooley, Diego M Presman, Sundar Ganesan, Rodney L Schiltz, Ashwini Sheshasayee, Valeria Levi, Ozlem Keskin, Stafford L Lightman and Gordon L Hager


11â-HSD1 Mediated Glucocorticoid Generation Impairs Brown Adipose Tissue Function in Ageing Mice
Emma Louise McCabe, Craig L Doig, Stuart Andrew Morgan, Agnieszka Ewa Zielinska, Dean Paul Larner, Jeremy W Tomlinson, Paul M Stewart and Gareth Geoffrey Lavery