"On the Edge of Glory" Innovative Predictors and Treatment of Metabolic Issues


Key Biological Pathways Causing Type 2 Diabetes Determined By Cluster Analysis
Miriam S Udler, Jaegil Kim, Marcin von Grotthuss, Jason Flannick, Gaddy Getz and Jose C Florez


Plasma Biomarkers Predict Diabetic Kidney Disease (DKD) in Adults with Type 1 Diabetes (T1D) over a 12-Year Follow-up: Cacti Study
Petter Bjornstad, Richard J Johnson, Laura Pyle, Rachel Sippl, Randy Wong, Marian Rewers and Janet K Snell-Bergeon


The Urinary Steroid Metabolome As a Novel Non-Invasive Tool to Stage Non-Alcoholic Fatty Liver Disease
Ahmad Moolla, Amin Amin, Beverly Hughes, Wiebke Arlt, Zaki Hassan-Smith, Lorna Gilligan, Matt Armstrong, Philip Newsome, Tahir Shah, Luc Van Gaal, An Verrijken, Sven Francque, Jane Grove, Neil Guha, Guruprasad Aithal, Ellie Barnes, Michael Biehl and Jeremy W Tomlinson


Efficacy of Metreleptin Therapy in the Treatment of Fatty Liver Disease Associated with Partial Lipodystrophy
Nevin Ajluni, Rasimcan Meral, Adam H Neidert, Diana Rus, Rita Hench, Thomas L Chenevert, Barbara McKenna, Frank DiPaola, Hari Conjeevaram and Elif A Oral


Exenatide Prevents Fat Accumulation in Liver By Inducing Hepatic CEACAM1 Expression Via a PPARγ-Dependent Mechanism
Hilda E Ghadieh, Harrison T Muturi, Christopher C Marino, Saja S Khuder, Lucia Russo, Zachary N Smiley, Julie C Hanna, Cara Gatto-Weis, Garrett Heinrich and Sonia M Najjar


Visceral Fat Reduction Is Associated with Improved Liver Transaminases in HIV-Infected Patients Treated with the GHRH Analogue Tesamorelin
Lindsay T. Fourman, Natalia Czerwonka, Meghan N. Feldpausch, Jean-Claude Mamputu, Julian Falutz, Josée Morin, Christian Marsolais, Takara L. Stanley and Steven K. Grinspoon