Late Breaking Developments in Female Reproduction and Menopause Treatment


The Role of Arcuate Nucleus Kisspeptin Neurons in the Generation of Luteinising Hormone Pulses
Jenny Clarkson, Su Young Han, Richard Piet, Robert Porteous, Timothy McLennan, William H Colledge and Allan E. Herbison


RF-Amide Related Peptide Neurons Are Required for Stress-Induced Suppression of LH Pulses and the Preovulatory LH Surg
Greg M Anderson, Shaun M Stowe, David A Timajo, George ADP Connolly, Joon S Kim and Saagar Patel


Overexpression of Mkrn3 Results in Delayed Pubertal Onset in Mice
Stephanie A. Roberts, Soukayna Chouman, Han Kyeol Kim, Victor M. Navarro, Patrick Everett Chappell, Rona S. Carroll and Ursula B Kaiser


Replenish Trial: 17β-Estradiol and Progesterone Combined in a Single Capsule (TX-001HR) Significantly Improved Moderate-to-Severe Hot Flushes in Postmenopausal Women
Roger A Lobo, David F Archer, Risa Kagan, Ginger D Constantine, Shelli Graham, Brian Bernick and Sebastian Mirkin


Clinical Evaluation of the NK3 Receptor Antagonist Fezolinetant (a.k.a. ESN364) for the Treatment of Menopausal Hot Flashes
Graeme L Fraser, Herman Depypere, Dirk Timmerman, Gilbert Donders, Peter Sieprath, Steven Ramael, Jean Combalbert and Hamid R Hoveyda


Neurokinin 3 Receptor Antagonism As a Novel Treatment for Menopausal Hot Flushes: A Phase 2, Randomised, Double-Blind, Placebo-Controlled Trial
Julia K Prague, Rachel E Roberts, Alexander N Comninos, Sophie A Clarke, Channa N Jayasena, Zachary Nash, Chedie Doyle, Deborah A Papadopoulou, Stephen R Bloom, Pharis Mohideen, Nicholas Panay, Myra Hunter, Johannes Veldhuis, Lorraine Webber, Les Huson and Waljit S Dhillo