Novel Mechanisms and Therapeutic Targets for Hormone-dependent Tumors

OR40-2

Progesterone Receptor Regulates Pathways Potentially Important for Progression of Ductal Carcinoma in Situ of the Breast
Hugo Villanueva, Sandra L. Grimm, Celetta G. Callaway, Alejandro Contreras, Kimal Rajapakshe, Shixia Huang, Cristian Coarfa, Sean Michael Hartig and Dean P. Edwards

OR40-3

Constitutively Active Mutant Estrogen Receptors in Breast Cancer Show Differential Responsiveness to Structurally Novel Antiestrogens
Yuechao Zhao, Valeria Sanabria Guillen, Mary Jo Laws, Yvonne S Ziegler, Ping Gong, Jian Min, Abhishek Sharma, Sung Hoon Kim, David Chu, Ben Ho Park, Steffi Oesterreich, David J Shapiro, Kendall W Nettles, John A Katzenellenbogen and Benita S Katzenellenbogen

OR40-4

Hormone-Sensitive Prostate Cancer from Men with Germline BRCA2 Mutations Has Increased Genomic Instability and a Mutational Profile That More Closely Resembles Castrate-Resistant Disease
Renea A Taylor, Heather Thorne, Mitchell Lawrence, Michael Fraser, Julie Livingstone, Shadrielle Melijah Espiritu, Declan Murphy, Mark Frydenberg, Damien Bolton, David Clouston, Paul Boutros, Robert Bristow and Gail P Risbridger

OR40-5

Lipid Catabolism Inhibition Sensitizes Prostate Cancer Cells to Antiandrogen Blockade
Isabel Rubio Schlaepfer, Maren Salzmann-Sullivan, Lih-Jen Su, Molishree Joshi, Miguel A. Gijon, Jihye Kim, Adrie Van Bokhoven, M.Scott Lucia, Francisco G. La rosa and Thomas W. Flaig

OR40-6

Arginine Vasopressin Receptor 1A as a Novel Therapeutic Target for Castration-Resistant Prostate Cancer
Ning Zhao, Stephanie O. Peacock, Chen Hao Lo, Meghan A. Rice, Laine Heidman, Ann M. Greene, Yushan Zhang, Yehia Daaka, Conor Lynch and Kerry L Burnstein