"As EU policymakers prepare proposals for the revisions of EU legislation, including the REACH chemicals regulation and cosmetics regulation, alongside a proposed ban on per and polyfluoroalkyl substances (PFAS), we, the European Society for Paediatric Endocrinology, the Endocrine Society and the European Society of Endocrinology, call on you to take this unique opportunity to prioritise protection of human health by limiting exposure to endocrine-disrupting chemicals (EDCs). Our societies represent the field of endocrinology, and our members are scientists and clinicians at the leading edge of advancing discoveries and clinical practice related to the endocrine system. In this letter we describe the primary reasons why stronger EU regulation is needed to effectively reduce the current high exposure to EDCs of the European population, and issue specific recommendations to reduce exposure."