TO: Office of Management and Budget (OMB)
RE: Comment on Proposed Revisions to 2 CFR Part 200
Submitted to regulations.gov docket OMB-2026-0034
The Endocrine Society submits these comments to express strong objection to the Office of Management and Budget’s proposed revisions to 2 CFR Part 200, the Regulation for Federal Financial Assistance, also called the Uniform Guidance. The Endocrine Society is the world’s oldest, largest, and most active professional medical and specialty society representing more than 18,000 endocrinologists, endocrine scientists, and allied healthcare professionals who are dedicated to advancing hormone research and improving the lives of patients with endocrine disorders such as diabetes, obesity, thyroid disease, osteoporosis, and reproductive health conditions. Many of our members’ research programs rely on grants administered through federal agencies, including the National Institutes of Health (NIH), to support their research. We are deeply concerned that the proposed changes would adversely affect research and undermine the future of scientific advances critical to improving population health and health outcomes. We assert that the rule should be withdrawn and OMB’s approach should be entirely reconsidered.