W. Lee Kraus, PhD

November 07, 2022

Dr. W. Lee Kraus is Professor and Director of the Green Center for Reproductive Biology Sciences, an endowed basic science research center at UT Southwestern with a research focus on signaling, gene regulation, and genomics.  He also holds the Cecil H. and Ida Green Distinguished Chair in Reproductive Biology Sciences.  Prior to his move to UT Southwestern in 2010, he was on the faculty in the Department of Molecular Biology and Genetics at Cornell University, Ithaca, NY for 10 years, where he moved through the ranks from assistant professor to full professor.  Dr. Kraus serves in multiple additional roles at UT Southwestern that leverage his scientific knowledge and experience to broadly support the basic and translational research enterprises of the Center (as director), the Department of Obstetrics and Gynecology (as Vice Chair for Basic Sciences), the Simmons Comprehensive Cancer Center (as Assistant Director for Basic Science), and the University (as the inaugural Assistant Dean for Research Development).  Dr. Kraus has been a member of the Endocrine Society since 1993 and has served in multiple roles, including Basic Science Chair for the 2019 Annual Meeting and the Basic Science Advisory Group Chair.  Dr. Kraus is a molecular biologist and endocrinologist, who has made significant contributions to our understanding of the mechanisms by which steroid and NAD+ signaling pathways control gene expression.  His discoveries at the forefront of chromatin, transcriptional regulation, and genomics have increased our understanding of how signal-regulated transcription factors, coregulator complexes, and histone- and chromatin-modifying enzymes collaborate to modulate chromatin structure and gene expression in a variety of biological systems, from reproduction and metabolism to cancer and inflammation.  He has been active in these fields as a scientist, conference organizer, journal editor, editorial board member, frequent manuscript reviewer, mentor, and teacher.  Dr. Kraus has also been involved in biotech a cofounder of Ribon Therapeutics, Inc. and ARase Therapeutics, Inc.

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