Podcast Journal Club

Monitoring Estradiol and DHT to Predict Outcomes in Male Hypogonadism

April 21, 2022


Join us for our 2-year anniversary episode! Host Dr. Chase Hendrickson, Vanderbilt University Medical Center, regular contributor Dr. Rich Comi, Fellowship Program Director and Section Chief for Endocrinology at Dartmouth Hitchcock Medical Center, and male reproduction expert Dr. Mathis Grossman, Professor of Medicine at the University of Melbourne and head of Andrology at Austin Health, discuss an article from the January 2022 edition of The Journal of Clinical Endocrinology & Metabolism (JCEM), “Relation of Testosterone, Dihydrotestosterone, and Estradiol with Changes in Outcomes Measures in the Testosterone Trials.”

Meet the Speakers

Mathis Grossmann and Richard Comi

Mathis Grossmann, MD, PhD, FRACP, is a physician-scientist trained in both basic biology and in clinical endocrinology. He is Professor of Medicine at the Department of Medicine, University of Melbourne, Australia, and head of Andrology at Austin Health, a tertiary academic centre. Dr. Grossmann graduated with an MD from Heidelberg University Medical School and did his internship in Munich, Germany. He then spent 4 years in basic research at the National Institutes of Health, USA, and obtained a PhD at the Walter and Eliza Hall Institute in Melbourne, followed by clinical training leading to FRACP. His research focuses on the roles of reproductive hormones in health and disease. His group conducts observational and interventional trials in men with i) low testosterone and chronic disease, ii) hypogonadism, iii) prostate cancer receiving androgen deprivation therapy, and iv) women with breast cancer receiving aromatase inhibition to understand how reproductive hormones regulate musculoskeletal health and glucose homeostasis, both at the clinical and the molecular level. He has ~200 peer reviewed publications and book chapters with more than 9,500 citations and a H-index of 52. Editorial board memberships include the Journal of Clinical Endocrinology and Metabolism, Journal of the Endocrine Society, Clinical Endocrinology (Oxford), Current Opinion in Endocrine and Metabolic Research, and he is Associate Editor of the European Journal of Endocrinology and of the Asian Journal of Andrology. Committee memberships include the US Endocrine Society Endocrine Self-Assessment Program (ESAP) and the Endocrine Society of Australia Council (Honorary Secretary).

Rich Comi, MD, is a Professor of Medicine at the Geisel School of Medicine at Dartmouth, Section Chief of Endocrinology and the Program Director for the endocrinology fellowship program at DHMC. Dr. Comi has been a member of the Department of Medicine at DHMC since 1989. He graduated from Harvard Medical School in 1980, completed his residency in Internal Medicine at the Massachusetts General Hospital in 1983 and did his fellowship in Endocrinology at the National Institutes of Health from 1983-1988. Dr. Comi has been instrumental in developing clinical programs in diabetes management at DHMC and in regional education outreach to disseminate best-practices of complex diabetic care. Dr. Comi was recognized in 2013 for his expertise and dedication to teaching by becoming a member of the Academy of Master Educators in the Geisel School of Medicine at Dartmouth.


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