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For our 76th episode, we discuss a recent Journal of Clinical Endocrinology & Metabolism secondary analysis examining pregnancy outcomes among women with polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM). Drawing on data from the DiGest randomized clinical trial, the study explores whether PCOS influences maternal and neonatal outcomes and whether a reduced-calorie dietary intervention benefits women with these coexisting metabolic conditions.
Host Chase Hendrickson, MD, MPH, MHCC, from Vanderbilt University, is joined by regular contributor Alison Myers, MD, from Albert Einstein College of Medicine and Montefiore Medical Center, along with guest expert Ellen Seely, MD, from Brigham and Women's Hospital and Harvard Medical School, to discuss "Association between polycystic ovary syndrome and pregnancy outcomes in GDM: A secondary analysis of the DiGest trial." Together, they examine the challenges of interpreting secondary analyses, the role of PCOS in pregnancy risk, the potential effects of dietary intervention in gestational diabetes, and what these findings mean for the clinical care of women with PCOS and GDM.
Regular Contributor
Alyson K. Myers, MD
Montefiore Einstein
Dr. Alyson K. Myers is a Professor of Medicine and the Associate Chair for Faculty Mentoring and Community Engagement for the Department of Medicine at Montefiore Einstein in the Bronx. She is also an adjunct Professor at the Zucker School of Medicine at Hofstra/Northwell, where she also served as the medical director of inpatient diabetes for North Shore University Hospital from 2013- 2021. Dr. Myers attended the University of Virginia where she majored in French and minored in Chemistry. She attended SUNY Downstate for medical school, where she was the four- year recipient of the President’s Award Scholarship. She completed a five-year combined Internal Medicine/Psychiatry Residency at Rush University Medical Center in Chicago, IL. During her fourth year, she was chief resident. After residency, she completed an endocrinology fellowship at the University of Texas Southwestern. During fellowship she received a T32 training grant in mood disorders and diabetes under the mentorship of Dr. Madhukar Trivedi.
In 2022, she was co-awarded a Center for Diabetes Translational Research grant to further examine and improve the health outcomes of people with diabetic foot ulcers. Her outcomes have been published in esteemed journals such as Endocrine Practice and the Journal of Foot and Ankle Surgery. She also leads the Montefiore Einstein multidisciplinary diabetic foot ulcer clinic which brings together the disciplines of endocrinology, infectious disease, vascular surgery, podiatry, and behavioral health. Dr. Myers is also involved with international efforts in countries such as Barbados and Jamaica for promoting foot care education and distributing proper footwear with OrthoFeet® and Samaritan’s Feet International through her organization DrSaveALimb, LLC. She is also a proud Silver Life Member of Alpha Kappa Alpha Sorority, Incorporated.
Guest Expert
Ellen Seely, MD
Brigham and Women’s Hospital
Ellen W. Seely, MD is an endocrinologist at Brigham and Women’s Hospital (BWH), where she serves as Director of Clinical Research for the Endocrinology, Diabetes and Hypertension Division and Professor of Medicine at Harvard Medical School (HMS). She has been studying the pregnancy complications of gestational diabetes and preeclampsia and their impact on future cardiometabolic health for over 25 years. Her research has been funded by NIH, the CDC and PCORI. She has served as the President of the Association of Patient Oriented Research, Chair of the Clinical Research Subcommittee of the Endocrine Society and is currently President of Women in Endocrinology. Clinically, she sees patients with endocrine complications preceding, during and following pregnancy. Dr. Seely has a long-term commitment to mentoring early career investigators recognized by 10 years of K24 funding from the NIH, a 2001 Clifford Barger Excellence in Mentoring Award from HMS, the 2017 Women in Endocrinology Mentoring Award, the 2017 Association for Clinical Translational Science Distinguished Educator Award, a 2022 William Silen Lifetime Achievement in Mentoring Award from HMS and will receive the 2025 Endocrine Society Mentor Laureate Award. Dr. Seely received her MD from Columbia College of Physicians and Surgeons in NYC and completed her training in internal medicine and endocrinology and metabolism at BWH.
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Meet the Host
Chase Hendrickson, MD, MPH, MMHC, practices general endocrinology at the Vanderbilt University Medical Center, where he is an associate program director for the endocrinology fellowship program. His interests include endocrine education, teaching inferential methods, and quality improvement.
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