Evaluation of Mean Platelet Volume and 25-Hydroxy Vitamin D Levels in Women with Gestational Diabetes

Presentation Number: SAT 328
Date of Presentation: April 2nd, 2016

Kadri Turan1, Mine Adas*2, Aysen Helvaci3, Murat Kahramaner4 and Muge Bilge5
1S.B Okmeydani Research and Training Hospital, 2Okmeydani Training Hospital, Istanbul, Turkey, 3SB Okmeydani Training Hospital, Turkey, 4S.B. Okmeydani Research and Training Hospital, 51SB Okmeydani Training Hospital, Istanbul, Turkey

Abstract

Background: Diabetes and pregnancy are both predisposing conditions for coagulation abnormalities, where increased mean platelet volume (MPV) and decreased vitamin D levels may play role. Studies, which evaluated MPV and 25-hydroxy vitamin D levels in women with gestational diabetes, have reported conflicting results.

Aim: To compare MPV and 25-hydroxy vitamin D values between gestational diabetic patients and healthy pregnant women.

Methods: The subjects were selected from 24-28 week-pregnant women who underwent gestational diabetes screening with oral glucose tolerance test. After the screening, 52 gestational diabetic patients and 52 healthy pregnant women were included in the study. MPV and vitamin D levels were recorded along with the demographic and clinical data of the subjects.

Results: Mean (standard deviation; SD) MPV was 8.5(1.0) fL and 8.3(1.1) fL in the gestational diabetic group and the control group, respectively. There was no statistically significant difference in the mean MPV value between the patient and the control groups (p=0.303). Mean (SD) 25-hydroxy vitamin D value was 20.5(11.0) ng/mL and 21.1(9.3) ng/mL in the gestational diabetic group and the control group, respectively. There was no statistically significant difference in the mean 25-hydroxy vitamin D levels between the patient and the control groups (p=0.477).

Conclusion: In this study, we did not detect a significant difference in MPV and 25-hydroxy vitamin D values between gestational diabetic and healthy pregnant groups.

 

Nothing to Disclose: KT, MA, AH, MK, MB