Connect with fellow experts – from bench to bedside – on the latest in adrenal and pituitary science and care. Engage with your peers in the SIG EndoForum in DocMatter subgroup.
Title: GH axis: Conditions and Biochemical Abnormalities Mimicking Acromegaly
Date: January 12, 2024 Time: 9:00 to 10:30 AM ET
Moderator:
Ismat Shafiq, MD Associate Professor of Medicine and Neurosurgery University of Rochester School of Medicine and Dentistry
Speakers:
Márta Korbonits, MD, PhD, DSc, FRCP Professor of Endocrinology and Metabolism Barts and the London School of Medicine and Dentistry, Queen Mary University of London
Pedro Marques, MD, PhD Pituitary Tumor Unit, Endocrinology Department, Hospital CUF Descobertas, Lisbon
Faculdade de Medicina, Universidade Católica Portuguesa, Lisbon, Portugal
Description:
Join our Adrenal Pituitary Special Interest Group for an insightful Webinar focusing on the nuances of the Growth Hormone (GH) axis. While clinical diagnosis of Acromegaly may seem straightforward, this webinar delves into situations where the patient exhibits acromegalic features despite normal growth hormone function. Similarly, we explore the complexities of biochemical testing for acromegaly, where variations in GH and Insulin-like growth-factor-1(IGF-1) levels may arise from physiologic, pathologic, and pharmacologic factors. Participate in this webinar to gain valuable knowledge that goes beyond the typical diagnostic criteria and enhance your ability to navigate the subtleties in the clinical and biochemical landscape of acromegalic presentations.
Learning Objectives:
Gain insights into the conditions that clinically resemble acromegaly.
Address Challenges and nuances in the diagnosis and management of conditions that mimic acromegaly.
Understanding the discrepancy between GH and IGF-1 due to pharmacologic, physiologic, and pathological causes.
Adrenal and Pituitary SIG Past Webinars
Adrenocortical Carcinoma: The Latest Pre-Clinical and Clinical Updates
February 17, 2023
Learning Objectives
Review the essential clinical features of adrenocortical carcinoma (ACC)
Discuss the translational research in ACC
Summarize treatment options for localized and advanced ACC
Speakers
Mouhammed Habra, Md, FACP, FACE
Professor
Chief, Section of Endocrine Neoplasia
Department of Endocrine Neoplasia and Hormonal Disorders
The University of Texas MD Anderson Cancer Center
Katja Kiseljak-Vassiliades, DO
Associate Professor
University of Colorado School of Medicine
Anschutz Medical Campus
Department of Internal Medicine
Division of Endocrinology, Metabolism and Diabetes
Moderator Inga Harbuz Miller, MD Assistant Professor University of Rochester
Adrenal Pituitary Special Interest Group held a September 23, 2022 webinar on the genetics of pituitary tumors. Gain knowledge of the mutations in patients with pituitary tumors and know when to consider genetic screening in various clinical scenarios.
Speaker:
Albert Beckers, MD, PhD
Chief of the Department of Endocrinology
University Hospital Centre, Liège
Professor
University of Liège
Moderators:
Niki Karavitaki, PhD, FRCP
Clinical Associate Professor
University of Birmingham
Honorary Consultant Endocrinologist
Queen Elizabeth Hospital Birmingham
Ismat Shafiq, MD
Endocrinologist,
Associate Professor
University of Rochester Medical Center
Learning Objectives:
Understand the genetic landscape in pituitary tumors.
Recognize the indications for genetic testing in patients with pituitary tumors.
Gain knowledge on the follow-up of patients with positive genetic testing.
Speakers: Nestoras Mathioudakis, MD, MHS Co-Medical Director, Associate Professor of Medicine, MHM Diabetes Prevention and Education Program, Johns Hopkins University of Medicine
Roberto Salvatori, MD Professor of Medicine and Medical Director Johns Hopkins University School of Medicine
Neelanjan Mukherjee, PhD Assistant Professor University of Colorado Anschutz Medical Center
Learning Objectives:
To describe the process of conducting machine learning research using large electronic health record data.
To recognize common types of machine learning algorithms used in healthcare and to understand how to compare performance of different models.
To review machine learning research and potential applications in the field of endocrinology.
The Adrenal/Pituitary Special Interest Group arranged small group discussions during ENDO 2021 on the challenging and illuminating experiences we have all shared since the outbreak of COVID-19. This event featured networking breakout sessions based on clinical and basic science interests. Attendees with adrenal and pituitary expertise had the opportunity to discuss the new normal during the pandemic. Clinical discussions covered topics such as adapting to telehealth, tele-education, and virtual labs. The research discussion highlighted issues including adapting to research life when facing new challenges including closed labs, limited opening of labs and clinical trials, writing papers/grants remotely, and teaching in the virtual world. In addition to considerations of the new difficulties presented, we also shared lessons learned and positive byproducts of working virtually.
Pituitary Microenvironment: The Science and the Clinical Implications
The Adrenal and Pituitary Special Interest Group held a webinar on the Pituitary Microenvironment: The Science and the Clinical Implications. The webinar featured Marta Korbonits, MD, PhD; Gerald Raverot, MD, PhD; Lauren Fishbein, MD, PhD; and Roberto Salvatori, MD.
Learning Objectives
Impact of the microenvironment in pituitary tumor behavior.
Therapeutic perspectives targeting the pituitary tumor microenvironment.
Mice models for in vivo studies will be discussed.
This webinar promoted critical review of published literature on adrenal and pituitary conditions and highlight publications which, according to the presenters, have impacted their clinical practice. It also enhanced knowledge and generated productive discussion on the topics covered, including:
The cardiovascular risk and mortality in patients with adrenal incidentaloma which is non-secreting or is associated with subclinical Cushing's;
The significance of ARMC5 gene defects in primary aldosteronism in clinical practice;
The consequences of Cushing's disease on long-term mortality and adjusting the approach in the long-term follow-up of these patients; and
The management options of thyrotropin-secreting pituitary adenomas.
Moderator: Lauren Fishbein, MD, PhD
Assistant Professor
University of Colorado School of Medicine
Speakers:
Ricardo Correa, MD, EdD
Program Director for Endocrinology
University of Arizona College of Medicine-Phoenix and Phoenix VAMC
Niki Karavitaki, MSc, PhD, FRCP
Senior Clinical Lecturer in Endocrinology
Institute of Metabolism and Systems Research (IMSR)
Hormone Measurements: An Update for the Clinical Endocrinologist
Speakers:
Hershel Raff, PhD, FAAAS, FAPS, Professor of Medicine, Surgery, and Physiology, Medical College of Wisconsin & Advocate Aurora Research Institute
Rashmi Mullur, MD, Associate Professor, David Geffen School of Medicine at UCLA
Rachel Webster, BSc (Hons) PhD FRCPath, Consultant Clinical Scientist, Trust Lead Scientist for Life Sciences, University of Birmingham
Moderators:
Niki Karavitaki, PhD, FRCP, Senior Clinical Lecturer, University of Birmingham
Sona Sharma, MD, Associate Professor of Medicine, Duke University,
Join the Adrenal Pituitary Special Interest Group for an update on hormone measurements. This webinar aims to cover topics on hormone measurements and their diagnostic cut-offs which are of practical value for the clinical endocrinologist. It also aims to enhance the understanding of endocrinologists on the impact of various herbs and supplements on the hypothalamo-pituitary-adrenal axis.
Speaker Topics:
“Updates on ACTH and cortisol measurement in clinical practice.” Speaker: Dr Hershel Raff.
“Impact of herbs and supplements on the HPA axis.” Speaker: Dr Rashmi Mullur.
“IGF-I, GH and PRL assays: what the endocrinologist needs to know.” Speaker: Dr Rachel Webster.
Learning Objectives:
Have clear understanding of the cut-offs of blood and salivary cortisol used in the diagnosis and follow-up of states of cortisol deficiency or excess.
Have insight on the assays used for ACTH, IGF-I, GH and prolactin measurements and their potential problems.
Understand the impact of herbs and supplements on the hypothalamo-pituitary-adrenal system.
Clinical Vignettes to Ask the Expert: Unique Cases of Pheochromocytoma/Paraganglioma
The Adrenal Pituitary SIG held a dialogue about unique cases of pheochromocytoma and paraganglioma. In this open discussion, endocrinology fellows presented complex cases of pheochromocytoma and paraganglioma and receive analysis and treatment recommendations from subject-matter experts.
Learning Objectives
Identify complex, atypical presentations of pheochromocytoma and learn the screening measures needed in these cases.
Determine the best options for case management and treatment for patients with ACTH producing pheochromocytoma.
Identify treatment options for metastatic and unresectable paragangliomas.
Expert Speaker: Karel Pacak, DSc, MD, PhD, Senior Investigator, NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development
Expert Speaker: Lauren Fishbein, MD, PhD, MTR, Assistant Professor in Medicine, University of Colorado School of Medicine Case
Presenter: Yumiko Esaki, MD, Internal Medicine and Pediatrics Resident, University of Rochester School of Medicine and Dentistry
Case Presenter: John Webster, DO, Endocrinology Fellow, University of Arizona College of Medicine
Moderator: Ricardo Correa, MD, EdD, University of Arizona, College of Medicine, Phoenix
Connect with fellow experts – from bench to bedside – on the latest in adrenal and pituitary science and care. Engage with your peers in the SIG EndoForum in DocMatter subgroup.