Collaborate, share, and expand knowledge and practice with neuroendocrinology leaders in the scientific, clinical, and translational arenas. SIG leaders plan to connect researchers and clinicians for a better understanding of research needs, leverage the Society’s unique position to act as a convening space for neuroendocrinology leaders, and develop resources for early career researchers and principal investigators in neuroendocrinology. Participate in educational, networking, and engagement activities, including webinars, event meetups, collaborative projects, and more.
Translating KNDy Neuron Biology into New Therapies
Date: Wednesday, April 30, 2025 Time: 12:00 PM ET (5:00 PM UK)
Moderators:
Denise Belsham, PhD, University of Toronto
Michael Lehman, PhD, Kent State University
Speaker:
Waljit Dhillo, FRCP, FMedSci, Imperial College London
Description:
Neurones which co-express Kisspeptin, neurokinin B and dynorphin (KNDy neurones) are the master regulators of GnRH secretion in the control of reproductive function. This webinar will highlight how translating these discovery science findings in humans has led to potential new treatments for patients with reproductive disorders.
Learning Objectives:
Objective 1: KNDy neurons are the master regulator of GnRH secretion
Objective 2: Kisspeptin stimulates GnRH secretion and has potential as a novel treatment for patients with reproductive disorders
Objective 3: Neurokinin B acting via the NK3 receptor mediates vasomotor symptoms in post-menopausal women and hence NK3R antagonists are a new target for treating this condition
Collaborate, share, and expand knowledge and practice with neuroendocrinology leaders in the scientific, clinical, and translational arenas. SIG leaders plan to connect researchers and clinicians for a better understanding of research needs, leverage the Society’s unique position to act as a convening space for neuroendocrinology leaders, and develop resources for early career researchers and principal investigators in neuroendocrinology. Participate in educational, networking, and engagement activities, including webinars, event meetups, collaborative projects, and more.