Endocrine-Disrupting Chemicals SIG

Date: Thursday, February 13, 2025
Moderator

• Aldo E. Calogero, MD, University of Catania, Catania, Italy

Speakers:

1. Federica Barbagallo, MD, University of Catania, Catania, Italy: EDC exposure and PCOS
2. Rossella Nappi, MD, PhD, University of Pavia, Pavia, Italy: Climate change and menopausal symptoms
3. Rossella Cannarella, MD, PhD, University of Catania, Catania, Italy: Which intervention to limit the exposure in reproductive age?
4. Questions & conclusive remarks Aldo E. Calogero 

Description:

This series of webinars aims to present the latest evidence on the impact of endocrine-disrupting chemical (EDC) exposure on gonadal function, examining both the effects of adult exposure and the long-term consequences of fetal exposure in the maternal environment. Specifically, the first webinar will focus on male gonadal function, while the second will address female gonadal function. The final session will offer evidence-based recommendations for practical interventions that can be incorporated into daily life and advised to patients. Relevant references will also be provided for those wishing to explore the topics in more depth.

Learning Objectives:

• Objective 1: Understand the impact of endocrine-disrupting chemicals (EDCs) on gonadal function: Examine the effects of both adult and fetal EDC exposure on male and female gonadal health, with a focus on the latest research findings.
• Objective 2: Explore gender-specific differences in EDC-related gonadal dysfunction: Gain in-depth knowledge of how EDC exposure affects male and female gonadal function differently, based on the evidence presented.
• Objective 3: Apply evidence-based interventions to mitigate the impact of EDCs: Learn practical, evidence-based recommendations for managing and reducing the risk of EDC exposure in daily life, with guidance on advising patients.

Date: Thursday, January 30, 2025
Moderator:

• Rossella Cannarella, MD, PhD, University of Catania, Catania, Italy
• Sandro La Vignera, MD, PhD, University of Catania, Catania, Italy

Speakers:

1. Aldo E. Calogero, MD, University of Catania, Catania, Italy: EDC and male infertility: Effects of adulthood exposure
2. Andrea Crafa, MD, University of Catania, Catania, Italy: EDC and male infertility: what about fetal exposure?  
3. Scott D. Lundy, MD, PhD, Cleveland Clinic, Cleveland, OH USA: EDC exposure and hypogonadism
4. Questions & conclusive remarks: Rossella Cannarella

Description and Learning Objectives

Date: Thursday, October 3, 2024

Moderator: Aldo E. Calogero, MD, University of Catania, Italy

Speakers:

1. Rossella Cannarella, MD, PhD, University of Catania, Italy (Overview of a systematic review and meta-analysis)
2. Andrea Crafa, MD, University of Catania, Italy (From systemic search to assessment of eligibility: the PRISMA flow chart)
3. Arcangelo Barbonetti, University of L'Aquila, Italy (Data extraction and statistical principles) 
4. Nicolás Garrido, IVIRMA Global Research Alliance, Spain (Assessment of quality of evidence)

Description: This webinar has been designed to support the scientific activity of the EDC SIG working groups. Several working groups are planning to conduct specific systematic reviews and meta-analyses on EDC topics covered by the SIG. The talks have been planned to provide a theoretical overview of this type of experimental design and a practical approach that can be useful to the group members during their work. Useful references will also be given to deepen the concepts provided during the webinar. 

Learning Objectives:

• Objective 1: Understand what is meant by systematic review and meta-analysis. A general overview of the essential components of this experimental design will be provided
• Objective 2: Provide practical ideas for carrying out a systematic review. The steps that make up a PRISMA flow diagram will be presented in detail
• Objective 3: Understand the statistical principles of meta-analysis, to clarify the characteristics of effective data extraction 

Date: Friday, September 20
Time: 12:30– 1:30 PM ET

Moderator: Rossella Cannarella, MD, PhD, University of Catania, Italy

Description: All Endocrine-Disrupting Chemicals (EDC) Special Interest Group (SIG) members are invited to participate in the upcoming town hall. This meeting aims to provide an overview of the working groups identified within the EDC SIG and their objectives, and to introduce members to the activities planned. The meeting will also allow members to provide their opinion on any specific topics they would like to be involved in. The EDC SIG Steering Committee is excited to meet you soon!

If you are not an EDC SIG member and would like to attend the town hall, please join the EDC SIG before registering for the event. This session will be in a meeting format (rather than a webinar).

Date: April 3, 2024

Moderator:
Marina Fernandez, PhD, Researcher IBYME-CONICET

Speakers:

• Robert Thomas Zoeller, MD, University of Massachusetts Amherst: How plastic chemicals affect the hypothalamic-pituitary-thyroid axis.
• Robert Sargis, MD, PhD, University of Illinois at Chicago: Plastic chemicals are obesogens and diabetogens.
• Leonardo Trasande, MD, MPP, NYU School of Medicine: What you can do with your patients to turn off the plastic tap and protect the endocrine system.
• Marina Fernandez, MSC, PhD, National Council for Scientific and Technical Research, Buenos Aires: Call for a global plastics treaty that protects endocrine health.

Description:

The rapidly increasing levels of plastic pollution represent a serious global environmental issue that negatively affects the environmental, social, economic and health dimensions of sustainable development. In February 2022, at the resumed fifth session of the United Nations Environment Assembly, a historic resolution was adopted to develop an international legally binding instrument on plastic pollution with the ambition to complete the negotiations by end of 2024. The session will review effects of EDCs from plastics in the endocrine system and the current state of the Plastics Treaty negotiations.

Learning Objectives:

• Objective 1: Revise EDC effects on the Endocrine System
• Objective 2: Understand how doctors can protect their patients
• Objective 3: Review current state of negotiations for the plastics treaty.

Male Reproduction and Endocrine-Disrupting Chemicals

Date/Time: Wednesday, March 8, 2023, 12:00-1:00 PM EST 

Speaker
Shanna Swan, PhD 
Professor of Environmental Medicine and Public Health 
Icahn School of Medicine at Mount Sinai 

Moderators:
Andrea Gore, PhD
Professor of Pharmacology and Toxicology 
University of Texas at Austin 

Jerry Heindel, PhD
Coordinator 
Healthy Environment and Endocrine Disruptor Strategies 

Learning Objectives:

• Understand the trends in multiple endpoints that signal declines in men’s reproductive health over the past 50 years.
• Learn how lifestyle and environment factors, particularly endocrine-disrupting chemicals (EDCs), contribute significantly to these trends.
• Recognize the ways that these declines impact current and future society and affect the long-term health of this and future generations.

Introduction to the Endocrine Disrupting Chemicals Special Interest Group

The Endocrine-Disrupting Chemicals SIG held this event on May 02, 2022, 2:00 PM - 3:00 PM EST. 

Details: The Endocrine Disrupting Chemicals SIG held this webinar to introduce the goals and motivation of the SIG. The science of endocrine disrupting chemicals has been a focus area for the Endocrine Society since 2005. This panel covers this history, and the importance of this research on different areas of health. Attendees received an update on the state of EDC regulations and gain insight on how they can become advocates for patients.

View recording.

The Role of Obesogens in the Obesity Epidemic 
Join the Endocrine Disrupting Chemicals SIG for a webinar on the role of obesogens in the obesity pandemic. The live event was held on 10/19/2022.

Speakers:
Raquel Chamorro-Garcia, PhD
Assistant Professor
University of California

Jerry Heindel, PhD
Director
Environmental Health Sciences Program,
Healthy Environment and Endocrine Disruptor Strategies

Robert Sargis, MD, PhD
Associate Professor of Medicine
University of Chicago

Moderator:
Tom Zoeller, PhD
Professor Emeritus of Biology
University of Massachusetts, Amherst

Learning Objectives

1. Learn what obesogens are and gain insight on the latest data supporting their role in obesity.
2. Discover the importance of transgenerational epigenetic inheritance of obesogens.
3. Overview the role of social and racial disparities in obesogen exposure and obesity.

View recording