Hypoglycemia, a dangerous drop in blood glucose levels related to insulin and sulfonylurea (SU) use, has been identified as one of the top three preventable adverse drug events by the U.S. Department of Health and Human Services. Yet the prevalence and high burden of disease in patients with type 2 diabetes (T2D), particularly the elderly, are often underappreciated in clinical settings. Supporting the early identification and management of those at greatest risk is critical.

The Endocrine Society has embarked on a multi-year quality improvement project, the Hypoglycemia Prevention Initiative, to design and test clinical interventions in primary care settings that will aim to decrease the number of patients at high-risk and the frequency and severity of their episodes.

Clinical Practice Guidelines

The Endocrine Society has developed the following evidence-based clinical practice guidelines to help clinicians identify patients at risk for hypoglycemic events and to improve the care of their patients with diabetes:


Government Resources

The federal government has developed information on preventing and treating hypoglycemia, including:


Endocrine News & Journals

Patient Resources

According to the National Institute of Diabetes and Digestive and Kidney Diseases: "Hypoglycemia, also called low blood glucose or low blood sugar, occurs when the level of glucose in your blood drops below normal. Symptoms of hypoglycemia tend to come on quickly and can vary from person to person...Sometimes people don’t feel any symptoms."

Find a diabetes education program in your area and talk with a doctor if you have symptoms of hypoglycemia, even if you only have one episode. For information on avoiding hypoglycemia, the link between diabetes & hypoglycemia, treatments, and non-diabetic hypoglycemia please visit Hormone.org. The Department of Veterans Affairs also has great information as part of the Hypoglycemia Safety Initiative.

KNOW HYPO Public Awareness Campaign from the Hormone Health Network, the Endocrine Society's public education arm.

Continuing Medical Education

The Endocrine Society provides continuing medical education for clinicians based on new evidence:


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